Evidence map›Paper›PMID 39946088›Full record

ArticleThe Journal of organic chemistry2025

Structural Effects on the Hydride-Tunneling Kinetic Isotope Effects of NADH/NAD

Ava Austin, Jessica Sager, Lauren Phan, Yun Lu

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ava AustinDepartment of Chemistry, Southern Illinois University Edwardsville, Edwardsville, Illinois 62026, United States.
Jessica SagerDepartment of Chemistry, Southern Illinois University Edwardsville, Edwardsville, Illinois 62026, United States.
Lauren PhanDepartment of Chemistry, Southern Illinois University Edwardsville, Edwardsville, Illinois 62026, United States.
Yun LuDepartment of Chemistry, Southern Illinois University Edwardsville, Edwardsville, Illinois 62026, United States.ORCID 0000-0002-3511-6041

Funding

Temperature Dependence of Hydride Kinetic Isotope Effects in Solution to Test the Proposed Role of Protein Dynamics in Enzyme CatalysisR15GM148951 · NIGMS · SOUTHERN ILLINOIS UNIV AT EDWARDSVILLE · PI LU, YUN · 2022 to 2022
$434k
NIGMS NIH HHS R15 GM148951
6 · The paper itself

Abstract

Contemporary H-tunneling theories predict that a longer donor-acceptor distance (DAD) corresponds to a larger kinetic isotope effect (KIE). Herein, hydride-tunneling reactions of NADH/NAD

Identifiers

PMID39946088
PMCPMC11877500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.