Evidence map›Paper›PMID 39946081›Full record

Observational studyEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2025

Children with unilateral molar-incisor hypomineralisation (MIH) may exhibit contralateral temporalis and masseter muscle hyperactivity: a cross-sectional study.

L M N Gonçalves, K F Molena, M R Carvalho, S C H Regalo, S Siéssere, F W G de Paula-Silva, A M de Queiroz, F K de Carvalho

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Association between molar-incisor hypomineralisation and occlusal alterations in children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L M N GonçalvesSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0003-0057-9430
K F MolenaSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-7290-8451
M R CarvalhoSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-5511-6073
S C H RegaloSchool of Dentistry of Ribeirão Preto (Department of Basic and Oral Biology), University of São Paulo, National Institute for Translational Medicine (INCT-TM), Ribeirão Pret, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4110-8299
S SiéssereSchool of Dentistry of Ribeirão Preto (Department of Basic and Oral Biology), University of São Paulo, National Institute for Translational Medicine (INCT-TM), Ribeirão Pret, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9756-3771
F W G de Paula-SilvaSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0001-8559-532X
A M de QueirozSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil. amqueiroz@forp.usp.br.ORCID http://orcid.org/0000-0003-2900-5000
F K de CarvalhoSchool of Dentistry of Ribeirão Preto (Department of Pediatric Dentistry), University of São Paulo, Av. do Café - Subsetor Oeste - 11 (N-11), Ribeirão Preto, São Paulo, 14040-904, Brazil.ORCID http://orcid.org/0000-0002-4837-0583

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/06978-9National Council for Scientific and Technological Development 405914/2021-0
6 · The paper itself

Abstract

purposeMolar-incisor hypomineralisation (MIH) impacts children's oral health and quality of life, but research on the stomatognathic system of unilateral cases, remains limited. This study evaluated the effects of unilateral MIH on the stomatognathic system in children, focusing on postural and masticatory activities and occlusal force contacts.

methodsIn this cross-sectional observational study, 28 children (mean age: 8.21 years) were divided into two groups: without MIH (CG) and with unilateral MIH (MIHG). Electromyography (EMG) evaluated the activity of masseter and temporalis muscles during various jaw postures and habitual chewing. Occlusal force contacts were measured using T-SCAN®. Comparisons were made between groups and sides. Statistical analysis employed the Shapiro-Wilk test, Wilcoxon signed-rank test, and paired t-test, with a significance level of 5%.

resultsEMG data demonstrated increased muscle hyperactivity in MIHG compared to CG at rest for the left temporalis muscle on the contralateral side (p < .001), during left laterality for the right temporalis muscle on the ipsilateral side (p = 0.04), and habitual chewing of soft food for the left temporalis muscle on the contralateral side (p = 0.02). Greater voluntary contraction was observed on the unaffected side in MIHG for the temporalis muscle at rest (p = 0.01) and the masseter muscle during right laterality (p = 0.02). No significant differences were found in occlusal force measurements between groups or sides.

conclusionsThis study indicates that unilateral MIH is associated with increased muscle hyperactivity in the contralateral temporalis and masseter muscles, without significant differences in occlusal force.

Indexed as

Dental Enamel HypoplasiaMasseter MuscleTemporal MuscleBite ForceChildCross-Sectional StudiesElectromyographyFemaleHumansMaleMasticationMolarMasticatory ForceMasticatory MusclesMolar incisor hypomineralisationOcclusal ForceSurface Electromyography

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.