Evidence map›Paper›PMID 39946068›Full record

Trial reportDigestive diseases and sciences2025

Prospective Video-Based Study Assessing Effect of Computer-Assisted Optical Diagnosis on Distinguishing Serrated, Hyperplastic, and Adenomatous Colorectal Polyps.

Dong Hyun Kim, Sofie Fournier, Edgard Medawar, Roupen Djinbachian, Mahsa Taghiakbari, Alan Barkun, Douglas K Rex, Heiko Pohl, Yutaka Saito, Amrita Sethi and 12 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Dong Hyun KimDepartment of Medicine, McGill University, Montréal, QC, Canada.
Sofie FournierDepartment of Medicine, McGill University, Montréal, QC, Canada.
Edgard MedawarCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Roupen DjinbachianCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Mahsa TaghiakbariCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Alan BarkunDivision of Gastroenterology, McGill University Health Centre, Montreal, QC, Canada.
Douglas K RexDivision of Gastroenterology and Hepatology, IN University Medical Center, Indianapolis, IN, USA.
Heiko PohlSection of Gastroenterology and Hepatology, VA Medical Center, White River Junction, VT, USA.
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Amrita SethiDivision of Digestive and Liver Disease, Irving Medical Center, Columbia University, New York, NY, USA.
Philip Wai Yan ChiuDepartment of Surgery, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Roberta MaselliDigestive Endoscopy Unit, Department of Gastroenterology, Division of Gastroenterology, Humanitas Clinical and Research Center and Humanitas University, Rozzano, Italy.
Mathieu PiocheService d'Hépato-Gastro-Entérologie et d'Endoscopie Digestive, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
Jeffrey MarksDepartment of Surgery, University Hospitals Cleveland Medical Center, Cleveland, USA.
Maher Al KhaldiCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Katarzyna PawlakThe Center for Therapeutic Endoscopy and Endoscopic Oncology, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Herawaty SebajangCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Florence BenardCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Roy HajjarCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Melissa Zarandi-NowrooziCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Frank SchwenterCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.
Daniel von RentelnCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada. daniel.von.renteln.med@ssss.gouv.qc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe current computer-aided diagnosis (CADx) systems are not trained to recognize sessile-serrated lesions (SSL) and currently classify SSL incorrectly either as hyperplastic or adenomatous. We aimed to assess the effect of current untrained CADx systems on diagnostic accuracy of SSL recognition among a diverse group of endoscopists.

methods17 endoscopists reviewed the same video and image series of 115 polyps [33% SL, 33% Hyperplastic Polyps (HP), and 34% tubular adenoma (TA)]. Presentation of polyps (SSL, TA, HP) was randomized with 50% of the polyps being displayed with a CADx diagnosis, and other 50% without.

resultsCADx identified 52.6% of SSL as HP and 47.4% as TA. CADx identified 68.4% of HP correctly and 82.1% of TA correctly. The accuracy of the endoscopists for SSL did not differ significantly when the CADx diagnosis was displayed compared to no CADx being displayed (64.1% vs 64.9%, p > 0.05). The diagnostic accuracy for HP and TA improved among endoscopists when a correct CADx diagnosis was displayed to the endoscopists compared to when no CADx information was displayed but worsened when the displayed CADx diagnosis was incorrect.

conclusionCurrent CADx systems when displaying correct diagnostic outputs for HP or TA improve diagnostic accuracy of the endoscopists. CADx systems not trained for SSL recognition do not significantly affect SSL recognition among endoscopists even if an incorrect diagnostic output (TA or HP) is displayed.

Indexed as

Adenomatous PolypsColonic PolypsColonoscopyColorectal NeoplasmsDiagnosis, Computer-AssistedAdenomaDiagnosis, DifferentialFemaleHumansHyperplasiaMaleMiddle AgedProspective StudiesVideo RecordingCADxComputer-assisted diagnosisOptical polyp diagnosisSerrated lesions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.