Evidence map›Paper›PMID 39946039›Full record

ReviewCurrent osteoporosis reports2025

Management of Bone Health in Adult Mastocytosis.

Yannick Degboé, Coralie Nezzar, Pauline Alary, Masson Maëva, Cristina Bulai Livideanu, Michel Laroche

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yannick DegboéRheumatology Department, CHU de Toulouse and Université de Toulouse, Toulouse, France. Degboe.y@chu-toulouse.fr.ORCID http://orcid.org/0000-0002-4293-8596
Coralie NezzarRheumatology Department, CHU de Toulouse and Université de Toulouse, Toulouse, France.
Pauline AlaryRheumatology Department, CHU de Toulouse and Université de Toulouse, Toulouse, France.
Masson MaëvaRheumatology Department, CHU de Toulouse and Université de Toulouse, Toulouse, France.
Cristina Bulai LivideanuMastocytosis Expert Centre - CEREMAST Toulouse, Toulouse, France.
Michel LarocheRheumatology Department, CHU de Toulouse and Université de Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe present review will examine bone disease in mastocytosis, analyze the existing literature on its management, and propose a strategy for osteoporosis treatment in systemic mastocytosis. This strategy is based on both the available scientific evidence and the experience gained at our expert center (CEREMAST). RECENT

findingsSystemic mastocytosis is a rare disorder, primarily affecting the bone and leading to osteoporosis, bone pain, and bone structural abnormalities. While traditionally described in indolent systemic mastocytosis, bone involvement is also observed in bone marrow mastocytosis. The true prevalence of systemic mastocytosis is likely underreported, highlighting the importance for clinicians to be familiar with the condition, particularly in cases of osteoporosis. Osteoporosis management typically involves bisphosphonates, with potential benefits from combining them with specific treatments like interferon in severe osteoporosis with vertebral fractures. The potential of new mast cell-targeting molecules to treat bone involvement needs to be demonstrated. This review provides a guide for osteoporosis and bone pain management in systemic mastocytosis.

Indexed as

Bone Density Conservation AgentsMastocytosis, SystemicOsteoporosisAdultDiphosphonatesHumansBone Density Conservation AgentsDiphosphonatesBisphosphonatesBoneFractureOsteoporosisSystemic mastocytosisTreatment

Identifiers

PMID39946039
PMCPMC11825596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.