Evidence map›Paper›PMID 39945987›Full record

ArticleJournal of fluorescence2025

Development of a Charge-Mediated Disaggregation-Induced Fluorescence Enhancement Platform Using NS-Carbon Dots for Metformin Quantification and Pharmacokinetic Studies.

Yousef A Bin Jardan, Mohamed M El-Wekil, Mohamed R Elmasry, Ashraf M Mahmoud, Al-Montaser Bellah H Ali

Abstract read
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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Mohamed M El-WekilDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt.
Mohamed R ElmasrySchool of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
Ashraf M MahmoudDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt.
Al-Montaser Bellah H AliDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt. Almontaser_bellah@aun.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel ratiometric fluorometric sensor has been developed utilizing dual-emission nitrogen and sulfur co-doped carbon dots (NS-CDs) for the sensitive determination of metformin. The sensing mechanism relies on a unique disaggregation phenomenon observed under acidic conditions, where electrostatic repulsion between positively charged NS-CDs and metformin molecules leads to enhanced fluorescence emission. Upon metformin addition, the NS-CDs exhibit differential enhancement of their characteristic emission peaks, with the 562 nm peak showing markedly greater amplification than the 365 nm peak. This distinctive response enabled the development of a ratiometric detection approach using the F

Indexed as

CarbonFluorescent DyesMetforminQuantum DotsAnimalsFluorescenceNitrogenRabbitsSpectrometry, FluorescenceSulfurCarbonFluorescent DyesMetforminNitrogenSulfurCarbon dotsDisaggregationMetforminPharmacokineticRatiometric

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.