Evidence map›Paper›PMID 39945763›Full record

ArticleJournal of agricultural and food chemistry2025

Taste-Guided Isolation of Bitter Compounds from the Mushroom

Lea M Schmitz, Tatjana Lang, Alexandra Steuer, Luisa Koppelmann, Antonella Di Pizio, Norbert Arnold, Maik Behrens

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Calcipostia guttulata (Basidiomycota, Polyporales) in Russia.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  4. Taste-Guided Isolation of Bitter Compounds from the MushroomJournal of agricultural and food chemistry · 2025
    Article
  5. Bitter taste receptors.Chemical senses · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lea M SchmitzLeibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany.
Tatjana LangLeibniz Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0002-5404-8814
Alexandra SteuerLeibniz Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.
Luisa KoppelmannLeibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany.
Antonella Di PizioLeibniz Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0002-8520-5165
Norbert ArnoldLeibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany.
Maik BehrensLeibniz Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0003-2082-8860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bitter taste perception cautions humans against the ingestion of potentially toxic compounds. However, current knowledge about natural bitter substances and their activation of human bitter taste receptors (TAS2Rs) is biased toward substances from flowering plants, whereas other sources are underrepresented. Although numerous mushrooms taste bitter, the corresponding substances and receptors are unexplored. Three previously undescribed triterpene glucosides, named oligoporins D-F, together with the known oligoporins A and B, were isolated from

Indexed as

AgaricalesPlant ExtractsReceptors, G-Protein-CoupledHEK293 CellsHumansMolecular StructureTasteTaste Receptors, Type 2Plant ExtractsReceptors, G-Protein-CoupledTaste Receptors, Type 2Amaropostia stipticabitter compoundsfungihuman bitter taste receptorstriterpene glycoside

Identifiers

PMID39945763
PMCPMC11869282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.