Evidence map›Paper›PMID 39945565›Full record

ArticlePediatric pulmonology2025

Risk Factors Associated With the Development of Late Pulmonary Artery Hypertension in Extremely Premature Infants.

Paige E Condit, John S Hokanson, Vivek Balasubramaniam, David J McCulley, Michael Lasarev, Luke Lamers, Ryan M McAdams, Dinushan C Kaluarachchi

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Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paige E ConditDivision of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID http://orcid.org/0000-0001-7682-7184
John S HokansonDivision of Pediatric Cardiology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Vivek BalasubramaniamDivision of Pediatric Pulmonology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
David J McCulleyDivision of Neonatology, Department of Pediatrics, University of California, San Diego, San Diego, California, USA.
Michael LasarevDepartment of Biostatistics and Informatics, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID http://orcid.org/0000-0002-1896-2705
Luke LamersDivision of Pediatric Cardiology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Ryan M McAdamsDivision of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Dinushan C KaluarachchiDivision of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

objectiveTo identify risk factors for late pulmonary artery hypertension (PH) at 36 weeks' postmenstrual age (PMA) in infants born before 28 weeks' gestation. DESIGN/

methodsA retrospective cohort study included infants born < 28 weeks' gestation who underwent PH screening echocardiography at 36 weeks' PMA. We compared characteristics between infants with and without late PH to determine associations.

resultsOf 99 infants, 20 (20%) developed late PH. The FiO2% requirement at 4 weeks of age, home oxygen use, and procedural patent ductus arteriosus closure were associated with late PH. Bronchopulmonary dysplasia (BPD) severity was linearly associated with late PH, with each 1-point increase in BPD severity corresponding to a 3.5-fold increased odds of late PH diagnosis. CONCLUSION(S): One in five extremely premature infants developed late PH. Markers of respiratory disease severity, including the BPD grade, were associated with the development of late PH.

Indexed as

Bronchopulmonary DysplasiaHypertension, PulmonaryInfant, Extremely PrematureDuctus Arteriosus, PatentEchocardiographyFemaleGestational AgeHumansInfant, NewbornMaleOxygen Inhalation TherapyRetrospective StudiesRisk FactorsSeverity of Illness Indexbronchopulmonary dysplasiaextreme prematuritypulmonary hypertension

Identifiers

PMID39945565
PMCPMC11823566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.