Evidence map›Paper›PMID 39945531›Full record

ArticleApplied and environmental microbiology2025

Autoinducer-2 signaling promotes intestinal colonization of

Yi Li, Shuo Han, Wenfang Niu, Chao Gao, Yuqi Wang, Mengyuan Qin, Jingjing Han, Xiaohua Xia, Hailei Wang

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yi LiCollege of Life Sciences, Henan Normal University, Xinxiang, China.ORCID 0000-0002-6537-8800
Shuo HanCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Wenfang NiuCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Chao GaoCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Yuqi WangCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Mengyuan QinCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Jingjing HanSchool of Medicine, Qingdao Huanghai University, Qingdao, China.
Xiaohua XiaCollege of Life Sciences, Henan Normal University, Xinxiang, China.
Hailei WangCollege of Life Sciences, Henan Normal University, Xinxiang, China.ORCID 0009-0006-0073-6319

Funding

MOST | National Natural Science Foundation of China (NSFC) 32000073
6 · The paper itself

Abstract

Quorum sensing systems, particularly autoinducer-2 (AI-2) signaling, have significant effects on bacterial colonization and virulence. However, how they affect intestinal colonization by pathogens and subsequent host immune responses remains unclear. Here, we investigated the influence of AI-2 signaling on the intestinal colonization ability of

Indexed as

Aeromonas veroniiApoptosisCypriniformesFish DiseasesGram-Negative Bacterial InfectionsHomoserineIntestinesLactonesAnimalsGastrointestinal MicrobiomeQuorum SensingSignal TransductionHomoserineLactonesN-octanoylhomoserine lactoneAeromonas veronii Z12autoinducer-2intestinal colonizationp53-mediated cell apoptosisreactive oxygen species

Identifiers

PMID39945531
PMCPMC11921386

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.