Evidence map›Paper›PMID 39945525›Full record

ArticlemSphere2025

Prophages are infrequently associated with antibiotic resistance in

Tony H Chang, Julie D Pourtois, Naomi L Haddock, Daisuke Furukawa, Kate E Kelly, Derek F Amanatullah, Elizabeth Burgener, Carlos Milla, Niaz Banaei, Paul L Bollyky

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Comparative genomics ofJournal of bacteriology · 2025
    Article
  7. Re-evaluating what makes a phage unsuitable for therapy.npj antimicrobials and resistance · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tony H Chang *Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-4227-6163
Julie D Pourtois *Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-6939-2909
Naomi L HaddockUniversity of California San Francisco Medical School, San Francisco, California, USA.
Daisuke FurukawaDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Kate E KellyDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Derek F AmanatullahDepartment of Orthopaedic Surgery, Stanford Hospital and Clinics, Redwood City, California, USA.
Elizabeth BurgenerDivision of Pediatric Pulmonology and Sleep Medicine, Children's Hospital Los Angeles, Keck School of Medicine at USC, Los Angeles, California, USA.
Carlos MillaCystic Fibrosis Clinic, Department of Medicine, Lucille Packard Children's Hospital, Stanford University School of Medicine, Stanford, California, USA.
Niaz BanaeiDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-8501-3000
Paul L BollykyDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Funding

MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0M
The role of macrophages in chronic suppurative otitis media associated sensory hearing lossR01DC019965 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peter Luke Santa Maria · 2022 to 2026
$3.6M
Non-invasive Monitoring for Infections and Rejection after Lung TransplantationR01AI182349 · NIAID · STANFORD UNIVERSITY · PI Paul L Bollyky · 2024 to 2026
$1.8M
Pathogenesis of Pf Bacteriophages in Pseudomonas Cystic Fibrosis lung InfectionsR01HL148184 · NHLBI · STANFORD UNIVERSITY · PI MILLA, CARLOS · 2019 to 2022
$1.7M
Hydrogel Delivery of Bacteriophage to Treat Wound InfectionsR01EB038154 · NIBIB · STANFORD UNIVERSITY · PI Paul L Bollyky, Ovijit Chaudhuri · 2025 to 2026
$1.2M
Studies on bacteriophages in respiratory diseasesK24AI166718 · NIAID · STANFORD UNIVERSITY · PI Paul L Bollyky · 2022 to 2026
$815k
Bacteriophage as a predictive biomarker in chronic Pseudomonas airway diseaseK23HL169902 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Elizabeth Bendig Burgener · 2023 to 2026
$796k
Antimicrobial peptides and antibiotic diffusion in sputumR21AI194044 · NIAID · STANFORD UNIVERSITY · PI BOLLYKY, PAUL L · 2025 to 2025
$424k
Cystic Fibrosis Foundation (CFF)Cystic Fibrosis Foundation (CFF) BURGEN23G0, BURGEN24A0-KBHHS | National Institutes of Health (NIH) 1K23HL169902-01HHS | National Institutes of Health (NIH) R01 HL148184-01, R01 AI12492093, R01 DC019965NHLBI NIH HHS K23 HL169902NHLBI NIH HHS R01 HL148184NIAID NIH HHS K24 AI166718NIAID NIH HHS R01 AI182349NIAID NIH HHS R21 AI194044NIAID NIH HHS T32 AI007290NIBIB NIH HHS R01 EB038154NIDCD NIH HHS R01 DC019965SU | Stanford Bio-X
6 · The paper itself

Abstract

Lysogenic bacteriophages can integrate their genome into the bacterial chromosome in the form of a prophage and can promote genetic transfer between bacterial strains

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialProphagesPseudomonas aeruginosaCystic FibrosisHumansMicrobial Sensitivity TestsPseudomonas InfectionsAnti-Bacterial Agentsantimicrobial activityantimicrobial safetybacteriophage geneticsbacteriophage therapy

Identifiers

PMID39945525
PMCPMC11934324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.