Evidence map›Paper›PMID 39945517›Full record

ArticleMicrobiology spectrum2025

Comparison of pharyngeal and invasive isolates of

Joseph J Zeppa, Ellen G Avery, Patryk Aftanas, Erin Choi, Simone Uleckas, Prachi Patel, Nicholas Waglechner, Hubert Jimenez, Christie Vermeiren, Kevin Katz and 3 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Comparing virulence profile of dominantInfectious diseases & immunity · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joseph J ZeppaDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Ellen G AveryDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Patryk AftanasShared Hospital Laboratory, Toronto, Ontario, Canada.
Erin ChoiShared Hospital Laboratory, Toronto, Ontario, Canada.
Simone UleckasShared Hospital Laboratory, Toronto, Ontario, Canada.
Prachi PatelShared Hospital Laboratory, Toronto, Ontario, Canada.
Nicholas WaglechnerShared Hospital Laboratory, Toronto, Ontario, Canada.ORCID 0000-0003-1758-1158
Hubert JimenezShared Hospital Laboratory, Toronto, Ontario, Canada.
Christie VermeirenDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Kevin KatzDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Xena X LiShared Hospital Laboratory, Toronto, Ontario, Canada.
Finlay Maguire *Shared Hospital Laboratory, Toronto, Ontario, Canada.ORCID 0000-0002-1203-9514
Robert Kozak *Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-6159-9972

Funding

University of Toronto (UofT) EPIC Ignite award
6 · The paper itself

Abstract

Invasive Group A streptococcal (iGAS) infections are rising in Canada and wordwide. The 2022-2023 Ontario iGAS season was among the highest recorded, a trend continuing in 2023-2024. We sequenced 38 invasive (blood) and 117 non-invasive (pharyngeal)

Indexed as

PharynxStreptococcal InfectionsStreptococcus pyogenesWhole Genome SequencingAdultAntigens, BacterialCanadaFemaleGenome, BacterialHumansMaleMiddle AgedOntarioVirulence FactorsAntigens, BacterialVirulence Factorsnon-invasive isolatespathogenesisStreptococcus pyogenesvirulence factorswhole-genome sequencing

Identifiers

PMID39945517
PMCPMC11960128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.