SynthesisActa paediatrica (Oslo, Norway : 1992)2025
Robin Sequence: From Dilemmas to Developing an Adaptable Standardized Stepwise Approach.
Synthesis in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Feasibility and clinical utility of daytime polysomnography performed in NICU to diagnose sleep disordered breathing in infants.BMJ paediatrics open · 2025Observational
- Do explainable AI (XAI) methods improve the acceptance of AI in clinical practice? An evaluation of XAI methods on Gleason grading.The journal of pathology. Clinical research · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
aimTo review the literature to identify key issues causing variation in clinical practice, assess the knowledge gap, and develop a standardised pathway for managing upper airway obstruction (UAO) in infants with Robin sequence (RS).
methodsThe tripartite framework of evidence-based practice, which included a systematic review of the literature, extensive consultation with a multidisciplinary team of experts, and feedback from the patients was used.
resultsOf the 2672 articles from the initial search, 66 were studied in detail. We identified five pivotal issues prevalent while managing UAO in RS. These issues were addressed systematically to develop an adaptable stepwise standardised pathway. The main pillars of the pathway are (a) early objective assessment of the severity of UAO using polysomnography, (b) graded treatment approach based on centre-specific preferences, (c) early and regular multidisciplinary team discussions and (d) clearly defined criteria for treatment escalation or cessation, discharge and follow-up.
conclusionThis unique pathway is based on available evidence, consensus of experts and parents' feedback. It provides a stepwise guide to the clinician for the management of UAO in infants with RS, adaptability for centre-specific treatment preferences and framework for future comparisons of different treatments.
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