Evidence map›Paper›PMID 39945069›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2025

Mechanotransduction in the Perivascular Adipose Tissue.

Stephanie W Watts, Teresa Krieger-Burke, Rance Nault, G Andres Contreras

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie W WattsDepartments of Pharmacology and Toxicology (S.W.W., T.K.-B., R.N.), Michigan State University, East Lansing.ORCID 0000-0002-9653-6357
Teresa Krieger-BurkeDepartments of Pharmacology and Toxicology (S.W.W., T.K.-B., R.N.), Michigan State University, East Lansing.ORCID 0000-0002-4846-9671
Rance NaultDepartments of Pharmacology and Toxicology (S.W.W., T.K.-B., R.N.), Michigan State University, East Lansing.ORCID 0000-0002-6822-4962
G Andres ContrerasLarge Animal Clinical Sciences (G.A.C.), Michigan State University, East Lansing.ORCID 0000-0003-4969-2178

Funding

The perivascular adipocyte: integrating mechanical and structural cues into vasoactive functionP01HL152951 · NHLBI · MICHIGAN STATE UNIVERSITY · PI Stephanie W Watts · 2022 to 2026
$13.3M
NHLBI NIH HHS P01 HL152951
6 · The paper itself

Abstract

Perivascular adipose tissue is of compelling interest when considering tissue mechanotransduction. Because of its location around a vessel, perivascular adipose tissue experiences from high (artery) to low (vein) pressures, pressures that are cyclical in nature. With blood pressure change, such as the elevation of pressure in hypertension, the question has been raised as to whether perivascular adipose tissue senses such changes, evidenced by a response that can be genetic, structural, or mechanical in nature. Here, we briefly review the following knowledge and data that support the ability of perivascular adipose tissue to both (mechano)sense and (mechano)respond.

Indexed as

Adipose TissueMechanotransduction, CellularAnimalsBlood PressureHumansHypertensionadipose tissuearteriesblood pressurehypertensionmechanotransduction, cellular

Identifiers

PMID39945069
PMCPMC11945577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.