ArticleFrontiers in nutrition2025
Higher levels of oxidative balance score linked to lower risk of gallstones: findings from the 2017-2020 National Health and Nutrition Examination Survey.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Article
- Association between serum carotenoid levels and gallstones in adults: a cross-sectional study using the National Health and Nutrition Examination Survey.Frontiers in nutrition · 2025Article
- Association between oxidative balance score and gallstone in US adults: a cross-sectional study.Frontiers in aging · 2025Article
- Machine learning-based prediction of recurrent extrahepatic bile duct stones after common bile duct exploration: a comparative study of models and SHAP-driven interpretability analysis.Frontiers in medicine · 2025Article
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5 authors.
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Abstract
Background and objective: The Oxidative Balance Score (OBS) has been linked to various chronic diseases; however, its association with gallstone prevalence remains underexplored. This study aimed to investigate the relationship between OBS and gallstone risk. Methods: This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2017 to March 2020. Weighted logistic regression models were applied to examine the association between OBS and the prevalence of gallstones, complemented by subgroup and sensitivity analyses. Restricted cubic spline (RCS) was used to investigate the nonlinear association between OBS and the prevalence of gallstones. Results: A total of 5,382 participants were included, among whom 592 reported a history of gallstones. After adjusting for confounding factors, a significant negative association was observed between OBS and gallstone prevalence (quartile 4 vs. quartile 1: odds ratio [OR] 0.63, 95% confidence interval [CI] 0.43-0.90, Conclusion: This study identified a significant negative linear association between OBS and gallstone risk, suggesting that higher OBS levels are associated with a reduced likelihood of gallstone formation.
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