Evidence map›Paper›PMID 39944881›Full record

ReviewQRB discovery2025

Frontiers in integrative structural modeling of macromolecular assemblies.

Kartik Majila, Shreyas Arvindekar, Muskaan Jindal, Shruthi Viswanath

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in QRB discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Evaluation of methods for AlphaFold-based integrative modeling.bioRxiv : the preprint server for biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kartik MajilaNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0009-0006-3190-7977
Shreyas ArvindekarNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0000-0002-9945-8534
Muskaan JindalNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0009-0005-2945-5345
Shruthi ViswanathNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0000-0002-9061-8407

Funding

XRAY CRYSTALLOGRAPHIC STRUCTURE ANALYSIS: PROTEIN SORTINGP41RR001081 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GODDARD, THOMAS · 1985 to 2011
$17.6M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
NCRR NIH HHS P41 RR001081NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

Integrative modeling enables structure determination for large macromolecular assemblies by combining data from multiple experiments with theoretical and computational predictions. Recent advancements in AI-based structure prediction and cryo electron-microscopy have sparked renewed enthusiasm for integrative modeling; structures from AI-based methods can be integrated with

Indexed as

Conformational ensemblesElectron cryo-tomographyGenerative modelingIntegrative modelingIntrinsically disordered proteinsMacromolecular assembliesProtein language models

Identifiers

PMID39944881
PMCPMC11811862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.