Evidence map›Paper›PMID 39944534›Full record

ArticleMaterials today. Bio2025

Brain neurons internalise polymeric micron-sized capsules: Insights from

Olga Kopach, Olga A Sindeeva, Kaiyu Zheng, Eleanor McGowan, Gleb B Sukhorukov, Dmitri A Rusakov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga KopachDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Olga A SindeevaSchool of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK.
Kaiyu ZhengDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Eleanor McGowanDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
Gleb B SukhorukovSchool of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK.
Dmitri A RusakovDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.

Funding

Medical Research Council MR/W019752/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/X001067/1Wellcome Trust 223131
6 · The paper itself

Abstract

Nanoengineered encapsulation presents a promising strategy for targeted drug delivery to specific regions in the body. While polyelectrolyte-based biodegradable microcapsules can achieve highly localised drug release in tissues and cell cultures, delivering drugs to intracellular sites in the brain remains a significant challenge. In this study, we utilized advanced imaging techniques, both

Indexed as

Brain neuronsBrain targetingInternalisationIntracellular deliveryPolyelectrolyte microcapsules

Identifiers

PMID39944534
PMCPMC11815287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.