Evidence map›Paper›PMID 39944513›Full record

ArticleBladder (San Francisco, Calif.)2024

Urethral bulking agents and pelvic floor muscle training for the treatment of stress urinary incontinence in female patients with multiple sclerosis.

Georgios Antoniadis, Ioannis Tsikopoulos, Aikaterini Tsionga, Konstantinos Galanoulis, Nikolaos Bousdroukis, Michael Samarinas

Abstract read
In one paragraph

Article in Bladder (San Francisco, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Georgios AntoniadisDepartment of Urology, General Hospital of Larissa, Tsakalof 1 Str, Larissa 41221, Greece.
Ioannis TsikopoulosDepartment of Neuro-urology, Royal National Orthopaedic Hospital, London W1W 5AQ, United Kingdom.
Aikaterini Tsionga1 Department of Urology, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54635, Greece.
Konstantinos GalanoulisDepartment of Urology, General Hospital of Larissa, Tsakalof 1 Str, Larissa 41221, Greece.
Nikolaos BousdroukisDepartment of Urology, General Hospital of Larissa, Tsakalof 1 Str, Larissa 41221, Greece.
Michael SamarinasNeuro-urology Clinic, General Hospital of Larissa, Tsakalof 1 Str, Larissa 41221, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stress urinary incontinence (SUI), characterized by involuntary urine leakage during increased abdominal pressure, is prevalent among women with multiple sclerosis (MS), significantly impacting their quality of life (QoL). Traditional treatments are less suitable for MS patients due to potential complications, highlighting the need for less invasive alternatives, Objective: This study assessed the effectiveness of UBAs and PFMT in managing SUI among female patients with MS. Methods: This nine-month study involved 14 female MS patients with moderate SUI, who were equally divided into two groups to evaluate the effectiveness of UBAs and PFMT. UBAs were administered through injections to enhance urethral resistance, while PFMT used guided exercises to improve pelvic control. Outcomes were assessed in terms of urinary pad usage, scores of International Consultation on Incontinence Questionnaire-Short Form, and QoL metrics to evaluate reductions in incontinence and symptom severity. Results: Both treatment groups showed significant improvement with SUI management. Daily pad usage decreased to 0-1 in both groups, with reductions in symptom severity and improvements in QoL scores. UBAs provided quicker symptomatic relief, while PFMT supported long-term management. However, two participants in the PFMT group discontinued follow-up due to MS-related complications, highlighting the challenges of maintaining adherence in progressive conditions. Conclusion: UBAs and PFMT are effective management options for SUI in MS patients, improving symptom control and QoL. This study underscored the importance of individualized, multimodal approaches to optimize outcomes for women with MS-related SUI. Nevertheless, further research is needed for long-term validation.

Indexed as

Multiple sclerosisPelvic floor Muscle trainingQuality of lifeStress urinary incontinenceUrethral bulking agents

Identifiers

PMID39944513
PMCPMC11810683

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.