ReviewAnnals of cardiothoracic surgery2025
Moderate controlled hypothermia
Review in Annals of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Gap between availability and utilization of cardiac donors: analysis of determining factors in Ecuador.Archivos peruanos de cardiologia y cirugia cardiovascularArticle
- Xenoperfusion-The Transformative Role of Machine Perfusion in Xenotransplantation.XenotransplantationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For most of the last almost 60 years of heart transplantation, static ice storage has been the dominant means of organ preservation. This method has allowed about 4 hours of relatively safe cold ischemic time, after which the risk of graft dysfunction increases exponentially. This limitation governed our allocation system and limited our ability to explore remote and extended criteria donors. Static-controlled hypothermia was recently introduced into clinical practice, and accumulating data demonstrate superior results with preservation when compared to ice storage. This has allowed centers to increasingly consider remote and extended criteria donors. Herein, we review the available data within the Global Utilization and Registry Database for Improved Heart Preservation (GUARDIAN-Heart Registry), supporting the expanding use of controlled, static preservation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.