Evidence map›Paper›PMID 39944493›Full record

ArticleFrontiers in medicine2025

Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters.

Nina Kemala Sari, Stepvia Stepvia, Muhana Fawwazy Ilyas, Siti Setiati, Kuntjoro Harimurti, Ika Fitriana

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. The Hallmarks of Aging: From Molecular Mechanisms to Clinical Translation.International journal of molecular sciences · 2026
    Review
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  4. The crossroads between osteosarcopenia and intrinsic capacity-a narrative review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nina Kemala SariGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.
Stepvia StepviaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.
Muhana Fawwazy IlyasFaculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
Siti SetiatiGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.
Kuntjoro HarimurtiGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.
Ika FitrianaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The aging process is frequently associated with a decline in functional capacity, endurance, muscle quality, and overall quality of life. Examining aging-related biomarkers often requires significant time and financial resources, underscoring the need for a straightforward and practical indicator. This study aims to investigate the association between handgrip strength and aging-related laboratory parameters in the elderly population of Indonesia. Methods: A cross-sectional study was conducted involving 109 participants aged 60-82 years. Handgrip strength was measured using a Jamar hydraulic hand dynamometer and Jamar PLUS+ digital dynamometer. Aging-related laboratory biomarkers were defined as those indicating physiological aging processes. Results: The study revealed a significant association between handgrip strength and several aging-related laboratory parameters, including leukocyte count, absolute neutrophil count, absolute lymphocyte count, neutrophil/lymphocyte ratio, and erythrocyte sedimentation rate. Discussion: These findings suggest that handgrip strength could serve as a cost-effective, non-invasive predictor of aging-related health status in older adults. Its practical utility highlights its potential for guiding health interventions targeting the elderly population.

Indexed as

agingbiomarkerselderly populationfunctional capacityhandgrip strength

Identifiers

PMID39944493
PMCPMC11814436

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.