ArticleFrontiers in bioengineering and biotechnology2024
Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics.
Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Thoracolumbar fascia ultrasound and elastography biomarkers in low back pain: a systematic review of associations and responsiveness to intervention.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Effects of Crew Seat Inclination on Multi-Organ Injury Risk in Astronauts During Off-Nominal High-g Landing Impact.Annals of biomedical engineering · 2026Article
- Foot Progression Angle Modulates Knee Loading During Walking in Individuals with Flexible Flatfoot.Annals of biomedical engineering · 2026Article
- Personalized 3D-Printed Finger Splints Derived from CT Data Incorporating Multi-Drug Bilayer Nanofiber Delivery Systems.AAPS PharmSciTech · 2026Article
- Advancing the 3Rs in bone tissue engineering: emergingFrontiers in physiology · 2026Review
- Comprehensive evaluation of critical-size calvarial defect in athymic rat model.Frontiers in physiology · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
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Abstract
Critical-size bone defects (CSDs), which are those that do not self-repair in a given period, are essential for evaluating bone-regeneration strategies. We established CSDs models in the rabbit cranium and ulna, and the bone-regeneration capacities of porous calcium phosphate (CaP) ceramics were assessed. A 12.6-mm cranial defect was confirmed as a CSDs after 12 weeks, with submicron surface-structured biphasic calcium-phosphate (BCP) implants [consisting of 20% hydroxyapatite and 80% tricalcium phosphate (TCP)] demonstrating significantly higher bone formation (32.2% ± 10.6%) than micron surface-structured TCP (TCP-B) implants (17.8% ± 4.6%,
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