ArticleQuantitative plant biology2025
Microtubule flexibility, microtubule-based nucleation and ROP pattern co-alignment enhance protoxylem microtubule patterning.
Article in Quantitative plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Conflicting roles of cell geometry, microtubule deflection, and orientation-dependent dynamic instability in cortical array organization.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The role of VND transcription factors in xylem vessel development and secondary wall formation.The New phytologist · 2025Review
- Microtubule-based nucleation results in a large sensitivity to cell geometry of the plant cortical array.PLoS computational biology · 2025Article
- Agent-based simulation of cortical microtubule band movement in arabidopsis zygotes.Scientific reports · 2025Article
- Impact factor: Playing a number on you.Quantitative plant biology · 2025Article
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Authors and funding
5 authors.
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Abstract
The development of the water transporting xylem tissue in plants involves an intricate interplay of Rho-of-Plants (ROP) proteins and cortical microtubules to generate highly functional secondary cell wall patterns, such as the ringed or spiral patterns in early-developing protoxylem. We study the requirements of protoxylem microtubule band formation with simulations in CorticalSim, extended to include finite microtubule persistence length and a novel algorithm for microtubule-based nucleation. We find that microtubule flexibility facilitates pattern formation for all realistic degrees of mismatch between array and pattern orientation. At the same time, flexibility leads to more density loss, both from collisions and the microtubule-hostile gap regions, making it harder to maintain microtubule bands. Microtubule-dependent nucleation helps to counteract this effect by gradually shifting nucleation from the gap regions to the bands as microtubules disappear from the gaps. Our results reveal mechanisms that can result in robust protoxylem band formation.
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