Evidence map›Paper›PMID 39944449›Full record

ReviewCureus2025

The Pharmacological and Clinical Roles of Antiemetics: A Narrative Review.

Alan D Kaye, Donovan B Turpin, Shivam Shah, Brennan Abbott, Alex V Hollander, Caroline R Burroughs, Sarah H Myers, Shahab Ahmadzadeh, Jibin Mathew, Adam M Kaye and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Donovan B TurpinSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Shivam ShahDepartment of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Brennan AbbottSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Alex V HollanderSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Caroline R BurroughsDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Sarah H MyersDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Jibin MathewDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Adam M KayeDepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Giustino VarrassiDepartment of Pain Medicine, Fondazione Paolo Procacci, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emesis (e.g., vomiting and nausea) can be a nebulous condition to treat, as it has many and highly varied etiologies. Understanding the underlying causes of emesis is crucial in selecting the appropriate antiemetic therapy. At present, there are a plethora of medications on the market to treat emesis, known as antiemetics. For the healthcare professionals managing emesis, key concerns include efficacy, the onset of effects, and potential adverse actions of these drugs. The present investigation reviews different classes of antiemetics and specific clinical uses for each based on pharmacological action. In addition, a few emerging treatment options are discussed, including cannabinoids, vitamin B6 (pyridoxine), and combination formulations such as Diclegis (doxylamine-pyridoxine), prompting avenues for future roles in the management of emesis.

Indexed as

antiemeticschemotherapygastroenteritismotion sicknessnauseavomiting

Identifiers

PMID39944449
PMCPMC11817452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.