ReviewCureus2025
The Effects of Magnesium Sulfate on Postoperative Pain in Patients Undergoing Lumbar Spinal Surgery: A Systematic Review of Randomized Controlled Trials.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnesium sulfate is commonly used intraoperatively to reduce postoperative pain in spinal surgery patients, but its effects when administered postoperatively are not well established. This study specifically aimed to assess the effect of magnesium sulfate on a postoperative basis on the incidence of postoperative pain in lumbar spinal surgery patients. This systematic review focuses on assessing the practicality of postoperative magnesium sulfate in the mitigation of pain after lumbar surgery. A comprehensive search was conducted across multiple databases, focusing on studies published between January 2000 and December 2023. The findings emphasize the significant role of magnesium in postoperative analgesia for adult patients undergoing lumbar spinal surgeries, with various administration routes explored, such as infusion, intravenous, or intramuscular. All in all, magnesium sulfate shows potential as an analgesic additive in lumbar surgery, aiding in postoperative pain reduction and decreased opioid use. However, its efficacy assessment is hindered by external variables. Standardized research is crucial to establish its optimal clinical applications and address knowledge gaps.
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