SynthesisFrontiers in pediatrics2025
The efficacy of parasacral transcutaneous electrical nerve stimulation for the treatment of overactive bladder in children: a systematic review and meta-analysis.
Synthesis in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Impact of Adjunctive Myo-Inositol and Magnesium Therapy on Paediatric Overactive Bladder: A Retrospective Analysis.Children (Basel, Switzerland) · 2026Article
- Electrical and Functional Magnetic Stimulation in the Management of Children's Lower Urinary Tract Dysfunction-A Current Literature Review.Children (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: Despite the presence of published evidence in recent decades suggesting an improvement in overactive bladder (OAB) with the utilization of parasacral transcutaneous electrical nerve stimulation (PTENS), there is currently a lack of consensus guidelines for therapy. We conducted a meta-analysis to assess the impact of PTENS on children with OAB. Methods: A search was carried out using EMBASE, PubMed, and the Cochrane Controlled Register of Trials to find eligible randomized controlled trials (RCTs) published up to 1 May 2023. From the literature review, eight RCTs (351 participants) comparing PTENS and other treatments (standard urotherapy/anticholinergics/biofeedback/placebo stimulation) were considered. Results: The overall complete response rate with PTENS was 1.90 times that of children undergoing other treatment (relative risk 1.90, 95% confidence interval 1.45-2.49). No significant differences were observed in the mean dysfunctional voiding score system ( Conclusions: In summary, PTENS has demonstrated better response rates and fewer side effects compared to conventional first-line treatments, such as standard urotherapy and antimuscarinic drugs. Clinicians should consider individual circumstances when treating children with OAB. However, it is important to note that the findings of this study are limited by the small sample size and imperfect outcomes. Further high-quality RCTs are needed to establish the most effective treatment protocol.
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