Clearing the AIR: A

Francisco J Bonilla-Escobar, Charlie Sawyer, Paul Yang, Kathryn L Pepple

Abstract readCase Reports

In one paragraph

Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francisco J Bonilla-EscobarDepartment of Ophthalmology, University of Washington, Seattle, WA, USA.

Charlie SawyerDepartment of Ophthalmology, University of Washington, Seattle, WA, USA.

Paul YangDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.

Kathryn L PeppleDepartment of Ophthalmology, University of Washington, Seattle, WA, USA.

Funding

Immune mechanisms of post-infectious uveitisR01EY030431 · NEI · UNIVERSITY OF WASHINGTON · PI PEPPLE, KATHRYN · 2019 to 2023

$2.2M

NEI NIH HHS R01 EY030431

6 · The paper itself

Abstract

Purpose: To detail the identification of a likely pathogenic variant in Observations: A 49-year-old woman with a history of systemic autoimmune disease presented with progressive peripheral vision loss, retinal vasculitis, and macular vitelliform lesions. The initial diagnosis of npAIR was later revised to an inherited retinal degeneration when her father was also found to be heterozygous for the same missense, likely pathogenic variant in the Conclusions and importance: The case of the proband underscores the diagnostic dilemma of differentiating npAIR from an IRD, especially in the presence of preexisting autoimmune disease. The identification of a likely pathogenic variant in

Indexed as

Autoimmune retinopathyGenetic testing in ophthalmologyInherited retinal degenerationIntravitreal steroidsPRPH2 mutationRetinal degenerationRetinal pigment epithelium degeneration

Identifiers

PMID39944181

DOI10.1016/j.ajoc.2025.102252

PMCPMC11815693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.