ArticleTherapeutic advances in reproductive health
Development of a predictive model for severe peripartum hemorrhage in placenta accreta spectrum cases under neuraxial anesthesia: a multicenter retrospective analysis.
Article in Therapeutic advances in reproductive health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The placenta accreta spectrum (PAS) represents a significant risk factor for severe postpartum hemorrhage. Recent studies have demonstrated the safety of neuraxial anesthesia (NA) in cesarean delivery (CD) for patients with PAS. Objectives: To evaluate the risk of severe peripartum hemorrhage in patients with PAS who underwent CD under NA. Design: A multicenter retrospective cohort study. Methods: This study analyzed 214 patients diagnosed with PAS. Logistic regression was used to identify factors increasing the risk of severe peripartum hemorrhage. A total of six machine learning (ML) algorithms were employed for model validation. Results: The predictive model includes the following risk factors: age at delivery >33 years ( Conclusion: A prenatal risk assessment model was developed to estimate the likelihood of severe peripartum hemorrhage in PAS patients undergoing CD under NA. This model may provide preliminary support for clinicians in tailoring anesthetic management strategies for potentially high-risk cases, but further studies are needed to confirm its clinical utility.
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