Evidence map›Paper›PMID 39944128›Full record

ArticleComputational and structural biotechnology journal2025

Systematic screening and dynamic profiling of germline regulatory pathways and spermatogonial surface markers in a bivalve mollusc.

Liangjie Liu, Ya Shu, Tian Liu, Huilan Wei, Yaxin Yang, Lijing Zhang, Xiaohui Ma, Guoqing Li, Yajuan Li, Shi Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liangjie LiuMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Ya ShuMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Tian LiuMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Huilan WeiMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Yaxin YangMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Lijing ZhangMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Xiaohui MaMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Guoqing LiMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Yajuan LiMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Shi WangMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.
Lingling ZhangMOE Key Laboratory of Marine Genetics and Breeding, Ocean University of China, Qingdao 266003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermatogonial cells are capable of transmitting genetic information to the next generation and have the potential for self-renewal. However, research on spermatogonial cells is generally limited by the paucity of cell surface markers, which are not universal among species. In this study, we developed a systematic screening strategy for germline regulatory pathways and spermatogonial surface markers in non-model organisms. This was achieved by combining weighted gene co-expression network analysis (WGCNA), differential expressed gene (DEG) overrepresentation analysis, and functional annotation. This strategy was employed to identify a spermatogonia-related module, which was found to be enriched with stem cell-related pathways in the scallop

Indexed as

FgfrPatinopecten yessoensisSpermatogonial cellsSurface markerWGCNA

Identifiers

PMID39944128
PMCPMC11814522

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.