Evidence map›Paper›PMID 39944047›Full record

ArticleFrontiers in psychology2025

Maternal singing and speech have beneficial effects on preterm infant's general movements at term equivalent age and at 3 months: an RCT.

Manuela Filippa, Gianluca Filippa, Elisa Della Casa, Alberto Berardi, Odoardo Picciolini, Sara Chiara Meloni, Clara Lunardi, Alessandra Cecchi, Alessandra Sansavini, Luigi Corvaglia and 3 more

Abstract read
In one paragraph

Article in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Manuela FilippaDepartment of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
Gianluca FilippaIndependent Researcher, Aosta, Italy.
Elisa Della CasaNeonatal Intensive Care Unit, Women's and Children's Health Department, University Hospital of Modena, Modena, Italy.
Alberto BerardiDepartment of Medical and Surgical Sciences of Mother, Children and Adults, University Hospital of Modena, Modena, Italy.
Odoardo PiccioliniPediatric Physical Medicine & Rehabilitation Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Sara Chiara MeloniPediatric Physical Medicine & Rehabilitation Unit, IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Clara LunardiDepartment of Neurosciences, Psychology, Drug Research and Child Health, Careggi University Hospital of Florence, Florence, Italy.
Alessandra CecchiDivision of Neonatology, Careggi University Hospital, School of Medicine, University of Florence, Florence, Italy.
Alessandra SansaviniDepartment of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.
Luigi CorvagliaNeonatal Intensive Care Unit, IRCCS AOU Bologna, Bologna, Italy.
Didier GrandjeanDepartment of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
EVC Group
Fabrizio FerrariDepartment of Medical and Surgical Sciences of Mother, Children and Adults, University Hospital of Modena, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: General Movements (GMs) are part of the spontaneous movement repertoire and assessing them helps to determine the integrity of the central nervous system in newborns. The aim of this study was to investigate the effects of maternal singing and speaking in the Neonatal Intensive Care Unit (NICU) on preterm infants' GMs at term equivalent age and at 3 months. Methods: In this multi-center randomized clinical trial, 56 stable preterm infants (25-32 weeks) were randomized to either an intervention group - in which mothers were asked to speak and sing to their infants for 20 min, 3 times per week, for 2 weeks - or to a control group. GMs were recorded both before and after the intervention - which took place at term equivalent age - and again at 3 months corrected age. The GMs were blindly coded based on the muted video tracks to produce both a general score and a detailed score. Results: Before the intervention, there were no significant differences between the two groups. The intervention wielded a significant effect on the GMs general score ( Conclusion: Live maternal singing and speaking are fundamental human practices that, in this study, enhanced preterm infants' general movements and potentially supported their neurobehavioral development. Integrating and supporting early vocal interaction into routine NICU care is crucial for at-risk populations.

Indexed as

early interventiongeneral movementsmaternal voiceprematuritysensorimotor system

Identifiers

PMID39944047
PMCPMC11815593

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.