Evidence map›Paper›PMID 39943978›Full record

ArticleJournal of contemporary brachytherapy2024

Development of GUI-based simple independent dose calculation software without DICOM data transfer for high-dose-rate brachytherapy.

Yuha Kim, Yang Sheng, Chunhao Wang, Ke Lu

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuha KimPanther Creek High School, Cary, North Carolina, USA.
Yang ShengDepartment of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA.
Chunhao WangDepartment of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA.
Ke LuDepartment of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Dose calculation in clinical treatment plans must be verified by an independent dose calculation prior to treatment. This study presented an independent second check dose calculation software developed for clinical use. Material and methods: A software developed using Python 3 tool on Google Colab platform enabled its deployment on standard computer systems. The software utilized AAPM TG-43 formalism and AAPM consensus dataset for TG-43 parameters, which were consistent with those of a commercial treatment planning system (TPS; Varian Brachy-Vision). As input, the software only used treatment plan report from TPS. Dosimetric comparisons were performed between software-calculated dose at reference points and corresponding TPS values across 117 clinical treatment plans (102 gynecological cases and 15 intra-operative radiation therapy [IORT] cases using high-dose-rate [HDR] brachytherapy). Gynecological cases were categorized into 12 applicator groups, depending on various combination of tandem, ovoids, and needles, and dose calculation points were manually selected close to prescribed dose. Results: 234 dose points (2 points per plan) were calculated. The dose discrepancy between software and TPS was -1% ±0.36% (mean ± standard deviation), with maximum of -3%. The accuracy of the software met AAPM guideline requirement (< 5% deviation). The simplicity of input file in graphical user interface (GUI) environment enabled the software to operate on any computer without additional software, data transfer, or manual data entry. This capability can be particularly advantageous in IORT procedures, which require quick turn-around second check without network connectivity to TPS for DICOM data transfer. Conclusions: A streamlined second check software using TG-43 formalism was developed in Python 3 tool and converted into independent executable GUI, to verify commercial TPS dose calculations in HDR brachytherapy. The software meets current practice guideline and is compatible with commonly used computer systems (Windows, MacOS, and Linux), requiring no additional software, manual data entry, or connection to TPS. The software will also be published online with free public access.

Indexed as

graphical user interface (GUI)HDR brachytherapyindependent second check dose calculationPython 3TG-43 formalism

Identifiers

PMID39943978
PMCPMC11812136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.