Evidence map›Paper›PMID 39943963›Full record

ArticleFrontiers in microbiology2024

The trend of phylogenetic and epitope variations of SARS-CoV-2 Omicron sub-lineages in Iran.

Mehdi Shabani, Ahmad Nejati, Jila Yavarian, Kaveh Sadeghi, Sevrin Zadheidar, Akram Sadat Ahmadi, Monire Ghadirali, Arghavan Zebardast, Adel Abedi, Mohammad Hossein Najmi and 2 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mehdi ShabaniDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ahmad NejatiDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Jila YavarianDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Kaveh SadeghiDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Sevrin ZadheidarDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Akram Sadat AhmadiDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Monire GhadiraliDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Arghavan ZebardastDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Adel AbediDepartment of Mathematics, Shahid Beheshti University, Tehran, Iran.
Mohammad Hossein NajmiDepartment of Bioinformatics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Nazanin-Zahra Shafiei-JandaghiDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Talat Mokhtari-AzadDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a significant public health issue worldwide in recent years. The most recently circulating variant of SARS-CoV-2, Omicron, and its rapid evolution into various sub-lineages have raised concerns regarding the effects of the immunity on the virus epitopes, in the human population. The present study evaluated and compared these important variations among different Omicron sub-lineages in Iran. Methodology: From October 2023 to August 2024, high coverage whole genome sequences of 49 SARS-CoV-2 strains were subjected to phylogenetic analysis and evaluation of B cell, CD4 Results: The phylogenetic tree exhibited eight Nextstrain clades (21L, 22F, 23B, 23H, 23D, 24A, 24B, and 24C) in 48 studied strains, and one recombinant strain (XDK.1). The evaluation of B cell, CD4 Conclusion: Herein, the increased conservation of CD8

Indexed as

epitope variationsimmunityOmicron sub-lineagesphylogeneticSARS-CoV-2

Identifiers

PMID39943963
PMCPMC11815659

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