A comprehensive study on postoperative complications and postoperative pancreatic fistula in sporadic non-functional pancreatic neuroendocrine tumors: A retrospective cohort study.

Juwan Kim, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Chang Moo Kang

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Article in Annals of hepato-biliary-pancreatic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Juwan KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0006-1507-336X

Seung Soo HongDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9913-8437

Sung Hyun KimDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7683-9687

Ho Kyoung HwangDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4064-7776

Chang Moo KangDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5382-4658

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds/Aims: Balancing surgical risks and benefits is crucial for managing non-functional pancreatic neuroendocrine tumors (NF-PNETs). Despite high postoperative pancreatic fistula (POPF) rates, studies on postoperative complications of sporadic NF-PNETs are scarce. Thus, this study aimed to investigate postoperative complications and identify risk factors for POPF. Methods: A retrospective review of 166 NF-PNET surgeries performed at Severance Hospital between February 2000 and August 2023 was conducted. Results: Age > 65 years and higher American Society of Anesthesiology (ASA) grade were not significantly correlated with severe complications (odds ratio [OR]: 1.10, Conclusions: Age and comorbidities had no significant impact on surgical outcomes. PD was associated with higher serious complications and POPF rates. The PT/MPD ratio is a valuable preoperative tool for predicting POPF risk in PD patients.

Indexed as

Gastro-enteropancreatic neuroendocrine tumorPancreatectomyPancreatic fistulaPostoperative complicationsRisk factors

Identifiers

PMID39943796

DOI10.14701/ahbps.24-215

PMCPMC12093232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.