Evidence map›Paper›PMID 39943776›Full record

ArticleStatistical methods in medical research2025

Robust propensity score estimation via loss function calibration.

Yimeng Shang, Yu-Han Chiu, Lan Kong

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yimeng ShangDepartment of Public Health Sciences, College of Medicine, The Pennsylvania State University, Hershey, PA, USA.ORCID 0000-0003-3770-4143
Yu-Han ChiuDepartment of Public Health Sciences, College of Medicine, The Pennsylvania State University, Hershey, PA, USA.
Lan KongDepartment of Public Health Sciences, College of Medicine, The Pennsylvania State University, Hershey, PA, USA.

Funding

Uncovering Heterogeneity in Individual Treatment Responses via Causal Machine LearningR35GM154888 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Yu-Han Chiu · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM154888
6 · The paper itself

Abstract

Propensity score estimation is often used as a preliminary step to estimate the average treatment effect with observational data. Nevertheless, misspecification of propensity score models undermines the validity of effect estimates in subsequent analyses. Prediction-based machine learning algorithms are increasingly used to estimate propensity scores to allow for more complex relationships between covariates. However, these approaches may not necessarily achieve covariates balancing. We propose a calibration-based method to better incorporate covariate balance properties in a general modeling framework. Specifically, we calibrate the loss function by adding a covariate imbalance penalty to standard parametric (e.g. logistic regressions) or machine learning models (e.g. neural networks). Our approach may mitigate the impact of model misspecification by explicitly taking into account the covariate balance in the propensity score estimation process. The empirical results show that the proposed method is robust to propensity score model misspecification. The integration of loss function calibration improves the balance of covariates and reduces the root-mean-square error of causal effect estimates. When the propensity score model is misspecified, the neural-network-based model yields the best estimator with less bias and smaller variance as compared to other methods considered.

Indexed as

Propensity ScoreAlgorithmsCalibrationHumansLogistic ModelsMachine LearningModels, StatisticalNeural Networks, ComputerCausal inferencecovariate balanceimbalance scoreinverse propensity score weightingmodel misspecificationneural networkobservational studies

Identifiers

PMID39943776
PMCPMC11951360

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.