Evidence map›Paper›PMID 39943158›Full record

ArticleAnimals : an open access journal from MDPI2025

Calcium Release-Activated Calcium Modulator ORAI1-Sensitive Serine Dehydratase Regulates Fatty Acid-Induced CD4

Bingbing Zhang, Jingjing Wang, Ming Li, Jianan Wen, Juan J Loor, Shuang Wang, Ziwei Ji, Xinquan Lv, Guihua Wang, Cheng Xia and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bingbing ZhangCollege of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.ORCID 0000-0002-1869-9652
Jingjing WangCollege of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Ming LiCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Jianan WenCollege of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Juan J LoorMammalian Nutri Physio Genomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0003-1586-4365
Shuang WangCollege of Animal Science, Ningxia University, Yinchuan 750021, China.
Ziwei JiCollege of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Xinquan LvCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Guihua WangCollege of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Cheng XiaCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Wei YangCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China.ORCID 0000-0003-3440-2190
Chuang XuCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

Funding

Post-doctoral Startup Foundation in Heilongjiang LBH-Q20051The National Natural Science Foundation of China 32172926, 32125038
6 · The paper itself

Abstract

High concentrations of free fatty acids (FFAs) caused by negative energy balance render the cow more prone to inflammatory diseases in part due to an imbalance in the types of immune cells and their specific functions. We previously demonstrated that ORAI calcium release-activated calcium modulator 1 (ORAI1) was associated with increased CD4

Indexed as

CD4+ T cellFOXP3high FFAIL-17ORAI1serine dehydratase

Identifiers

PMID39943158
PMCPMC11815743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.