Evidence map›Paper›PMID 39942925›Full record

ReviewPlants (Basel, Switzerland)2025

Red-Leafed Lettuces: Genetic Variation or Epigenetic Photomorphogenesis?

Natalya V Smirnova, Ivan A Timofeenko, Konstantin V Krutovsky

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalya V SmirnovaInstitute of Soil Science and Agrochemistry, Siberian Branch of the Russian Academy of Sciences, Prospect Lavrenteva 8/2, 630090 Novosibirsk, Russia.
Ivan A TimofeenkoInterdisciplinary Laboratory of City Farming, Institute of Gastronomy, Siberian Federal University, 660041 Krasnoyarsk, Russia.ORCID 0000-0002-4996-4674
Konstantin V KrutovskyInterdisciplinary Laboratory of City Farming, Institute of Gastronomy, Siberian Federal University, 660041 Krasnoyarsk, Russia.ORCID 0000-0002-8819-7084

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2024-682
6 · The paper itself

Abstract

Red-leaf lettuces, rich in bioactive compounds like anthocyanins and flavonoids, offer health benefits by reducing oxidative stress and boosting immunity. This article provides an extensive review of the genetic, epigenetic, environmental, and technological factors influencing anthocyanin biosynthesis and leaf coloration in red-leaf lettuce, emphasizing its significance in agriculture and nutrition. The genetics of anthocyanin biosynthesis, environmental influences, practical applications, agronomic insights, and future directions are the main areas covered. Anthocyanin accumulation is regulated by structural, regulatory, and transporter genes, as well as the MYB-bHLH-WD40 (MBW) complex. Mutations in these genes impact coloration and stress responses. Advances in genomic studies, such as GWAS and QTL mapping, have identified key genes and pathways involved in anthocyanin biosynthesis, aiding breeding programs for desirable traits. In addition, light intensity, stress conditions (e.g., drought, temperature), and phytohormones affect anthocyanin levels and photomorphogenesis in general. Controlled environments, like vertical farms, optimize these conditions to enhance pigmentation and phytochemical content. LED lighting and tailored cultivation techniques improve color intensity, antioxidant capacity, and yield in controlled settings. Sustainable production technologies for red-leaf lettuce in vertical farms are being developed to meet consumer demand and promote functional foods, integrating genetic, epigenetic, and environmental research into agronomy. This review highlights red-leaf lettuce's aesthetic, nutritional, and functional value, advocating for innovative cultivation methods to enhance its market and health potential.

Indexed as

anthocyaninsantioxidantsenvironmental factorsepigeneticsflavonoidsgene expressionlightphotomorphogenesisphytochemicalsred-leafed lettuces

Identifiers

PMID39942925
PMCPMC11819813

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.