Evidence map›Paper›PMID 39942621›Full record

ArticleMolecules (Basel, Switzerland)2025

Design, Synthesis, and Anti-Tyrosinase, Anti-Melanogenic, and Antioxidant Activities of Novel

Hyeon Seo Park, Hee Jin Jung, Hye Soo Park, Hye Jin Kim, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyeon Seo ParkDepartment of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Hee Jin JungDepartment of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-7212-5572
Hye Soo ParkDepartment of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Hye Jin KimDepartment of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Yujin ParkDepartment of Medicinal Chemistry, New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea.
Pusoon ChunCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae 50834, Republic of Korea.ORCID 0000-0002-7349-9880
Hae Young ChungDepartment of Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-3215-8828
Hyung Ryong MoonDepartment of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0003-1119-7112

Funding

Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education NRF-2021R1I1A1A01052284National Research Foundatioin of Korea (NRF) grant funded by the Korean government (MIST) NRF-2020R1A2C1004198
6 · The paper itself

Abstract

To discover novel anti-melanogenic compounds with tyrosinase inhibitory activity,

Indexed as

AntioxidantsDrug DesignEnzyme InhibitorsMonophenol MonooxygenaseThiazolidinesAgaricalesAnimalsCell Line, TumorHumansMelaninsMiceMolecular Docking SimulationMolecular StructurePyronesStructure-Activity RelationshipAntioxidantsEnzyme Inhibitorskojic acidMelaninsMonophenol MonooxygenasePyronesThiazolidinesB16F10 cellsmelanintyrosinase(Z)-BBTTβ-phenyl-α,β-unsaturated carbonyl

Identifiers

PMID39942621
PMCPMC11820736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.