Evidence map›Paper›PMID 39942608›Full record

ArticleMolecules (Basel, Switzerland)2025

Thermal Characterisation and Toxicity Profile of Potential Drugs from a Class of Disubstituted Heterofused Triazinones.

Małgorzata Sztanke, Renata Łyszczek, Agnieszka Ostasz, Halina Głuchowska, Krzysztof Sztanke

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Małgorzata SztankeDepartment of Medical Chemistry, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0003-1576-097X
Renata ŁyszczekDepartment of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, M.C. Skłodowskiej Sq. 2, 20-031 Lublin, Poland.
Agnieszka OstaszDepartment of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, M.C. Skłodowskiej Sq. 2, 20-031 Lublin, Poland.ORCID 0000-0002-5397-4103
Halina GłuchowskaDepartment of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, M.C. Skłodowskiej Sq. 2, 20-031 Lublin, Poland.
Krzysztof SztankeLaboratory of Bioorganic Compounds Synthesis and Analysis, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0002-1898-5245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thermal characterisation and toxicity profile of a class of disubstituted heterofused triazinones were revealed in this article for the first time. The thermal behaviour of molecules

Indexed as

TriazinesAnimalsAntineoplastic AgentsDrug StabilityEmbryo, NonmammalianErythrocytesFemaleHemolysisHot TemperatureHydrogen PeroxideMaleOxidative StressRatsRats, WistarToxicity TestsZebrafishAntineoplastic AgentsHydrogen PeroxideTriazinesantihaemolytic activitydisubstituted heterofused triazinonesdual-acting agentsin vivo and ex vivo toxicity profilepotential analgesicspotential anticancer agentsTG/DSCTG/FTIRthermal characterisationthermal degradation mode

Identifiers

PMID39942608
PMCPMC11821220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.