The Mechanical Properties, Corrosion Resistance, and Biocompatibility of a Novel Ternary Ti-xNb-5Ta Alloy for Biomedical Applications.

Haochen Wu, Tao Jiang, Linghui Kong, Xiaohong Chen, Ping Liu

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Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Haochen WuSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID 0000-0001-8387-6275

Tao JiangSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.

Linghui KongSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.

Xiaohong ChenSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.

Ping LiuSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, advancements in dental implants have posed new challenges for the use of traditional orthopedic materials. This study prepared novel Ti-xNb-5Ta alloys via arc-melting and comprehensively evaluated the effects of Nb content on microstructure, mechanical properties, elastic modulus, electrochemical behavior, and in vitro performance. Interestingly, alloys with different Nb contents exhibited distinct properties. The results indicated that the 10 and 13 wt.% Nb alloys surpassed the TA4G surgical implant standard in strength while offering a lower elastic modulus and greater elongation. Electrochemical experiments showed that the corrosion resistance of the alloys improved with increasing Nb content. Furthermore, CCK-8 assay results, ALP semi-quantitative analysis, and RT-PCR demonstrated that Ti-xNb-5Ta alloys enhanced the early osteogenic differentiation of human bone marrow stromal cells (hBMSCs). This work not only reveals the potential of Ti-xNb-5Ta alloys as biomedical materials but also offers insights for developing novel biomaterials.

Indexed as

biocompatible materialscorrosion resistanceearly osteogenic differentiationnear-β-type titanium alloyternary alloy

Identifiers

PMID39942268

DOI10.3390/ma18030602

PMCPMC11818253

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.