Evidence map›Paper›PMID 39942072›Full record

ArticleFoods (Basel, Switzerland)2025

Development and Evaluation of Gelatin-Based Gummy Jellies Enriched with Oregano Oil: Impact on Functional Properties and Controlled Release.

Mariana Ganea, Potra Cicalau Georgiana Ioana, Timea Claudia Ghitea, Liana Ștefan, Florina Groza, Olimpia Daniela Frent, Csaba Nagy, Claudiu Sorin Iova, Andrada Florina Schwarz-Madar, Gabriela Ciavoi and 3 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Emulgel withPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mariana GaneaPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0003-4643-2151
Potra Cicalau Georgiana IoanaDepartment of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0002-8412-104X
Timea Claudia GhiteaPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0001-8981-1958
Liana ȘtefanDepartment of Obstetrics and Gynecology, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Florina GrozaDepartment of Preclinics, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania.ORCID 0000-0002-8420-024X
Olimpia Daniela FrentPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0002-8865-3764
Csaba NagyDoctoral School of Biomedical Science, University of Oradea, No. 1 University Street, 410087 Oradea, Romania.ORCID 0009-0008-2375-9884
Claudiu Sorin IovaDepartment of Preclinics, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania.
Andrada Florina Schwarz-MadarDepartment of Obstetrics and Gynecology, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Gabriela CiavoiDepartment of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.ORCID 0000-0003-1417-5963
Laura Gratiela VicasPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0001-5328-333X
Pelea Diana ConstantaDepartment of Obstetrics and Gynecology, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0002-8862-4306
Corina MoisaPharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.

Funding

University of Oradea 410068
6 · The paper itself

Abstract

Functional foods play a crucial role in contemporary dietary strategies. This study investigates the incorporation of oregano oil, a bioactive extract that is known for its antimicrobial and antioxidant properties, into gelatin-based gummy jellies to develop functional food products with controlled release properties. The jellies were evaluated for mass uniformity, swelling index, disintegration time, and tensile strength under simulated oral and gastric conditions. The results showed that oregano oil significantly reduced the swelling index (e.g., 128.76 ± 0.67% at pH 5) and prolonged the disintegration time (e.g., 6-18 min across pH environments), highlighting its potential for controlled release. The mechanical strength remained stable (5.2 ± 0.3 N), ensuring structural integrity. These findings suggest that oregano-oil-enriched gummy jellies offer health benefits, although further studies are needed to explore their long-term stability and bioavailability.

Indexed as

bioactive compoundscontrolled releasedisintegration timefood formulationfunctional foodsgelatin-based jelliesnatural extractsoregano oilswelling indextensile strength

Identifiers

PMID39942072
PMCPMC11817771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.