Evidence map›Paper›PMID 39942056›Full record

ArticleFoods (Basel, Switzerland)2025

Influence of the β-Casein Genotype of Cow's Milk (A1, A2) on the Quality and β-Casomorphin-7 (BCM-7) Content of a Semi-Hard Cheese During Production.

Louisa Zinßius, Lucas Keuter, Carsten Krischek, Nadja Jessberger, Benedikt Cramer, Madeleine Plötz

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Louisa ZinßiusInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, 30173 Hannover, Germany.
Lucas KeuterInstitute of Food Chemistry, University of Münster, 48149 Münster, Germany.ORCID 0000-0002-6830-1550
Carsten KrischekInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, 30173 Hannover, Germany.
Nadja JessbergerInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, 30173 Hannover, Germany.
Benedikt CramerInstitute of Food Chemistry, University of Münster, 48149 Münster, Germany.ORCID 0000-0001-7632-8676
Madeleine PlötzInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, 30173 Hannover, Germany.

Funding

This IGF Project of the FEI (Research Association of the German Food Industry, Bonn, Germany) was supported within the program for promoting the Industrial Collective Research (IGF) of the German Ministry of Economics and Climate Action (BMWK), based on a AIF21953N
6 · The paper itself

Abstract

Cow's milk contains A1- and A2-β-caseins. The breakdown of A1-β-casein produces β-casomorphin-7 (BCM-7), a peptide with opioid-like properties that is associated with health aspects. In addition, A1- and A2-β-casein have different technological properties. The aim of the present study was to investigate whether cheese produced from the milk of homozygous A1A1 and A2A2 cows varies in terms of its physicochemical parameters and BCM-7 concentration. These parameters were analyzed during initial cheese processing, six weeks of ripening and 84 days of storage, including additional microbiological analyses during the storage period. The pH values of the A1A1 cheeses were higher than those of the A2A2 cheeses from the beginning of production until the starter culture bacteria were added. The yellowness values of the A1A1 cheeses were lower until the salt bath treatment. Water activity, lightness, hardness, fat, protein, NaCl and dry matter content, as well as color and microbiological parameters, were not affected by the β-casein genotype. BCM-7 concentrations were higher in the A1A1 cheeses after pressing and during ripening. We found mainly comparable quality characteristics and slightly different BCM-7 levels in the A1A1 and A2A2 cheeses. From this point of view, both varieties are equally suitable for cheese production.

Indexed as

A1-β-caseinA2-β-caseinbovine milkmicrobiological parametersphysicochemical parameterssemi-hard cheeseβ-casomorphin-7 (BCM-7)

Identifiers

PMID39942056
PMCPMC11817730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.