Evidence map›Paper›PMID 39941853›Full record

ArticleCancers2025

Analysis of Prognostic Factors for Internal Carotid Artery Invasion by Nasopharyngeal Carcinoma.

Ching-Feng Lien, Shyh-An Yeh, Chiu-Shih Cheng, Feng-Yu Chiang, Tzer-Zen Hwang, Bi-He Cai, Chih-Yi Liu, Hsu-Huei Weng, Chia-Chi Chen, Meng-Che Hsieh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ching-Feng LienDepartment of Otolaryngology-Head and Neck Surgery, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.
Shyh-An YehSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.
Chiu-Shih ChengDepartment of Neuroradiology, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.
Feng-Yu ChiangDepartment of Otolaryngology-Head and Neck Surgery, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.
Tzer-Zen HwangDepartment of Otolaryngology-Head and Neck Surgery, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0001-9841-9966
Bi-He CaiSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0003-4226-6096
Chih-Yi LiuNursing Department, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.
Hsu-Huei WengDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi, Chang Gung University College of Medicine, Taoyuan City 33302, Taiwan.ORCID 0000-0002-2020-8912
Chia-Chi ChenDepartment of Pathology, E-Da Hospital, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0002-4905-3408
Meng-Che HsiehSchool of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic impact of internal carotid artery (ICA) invasion in nasopharyngeal cancer (NPC) patients is not well established. Thus, we conducted a retrospective study to analyze the prognostic factors for ICA invasion by NPC.

methodsThis retrospective study included consecutive biopsy-proven NPC patients who received CCRT from November 2015 to December 2022 at E-Da Hospital. Patients were then classified into two groups according to ICA invasion by tumor or not. Survival was estimated by the Kaplan-Meier method with a five-year overall survival (OS) rate and five-year disease specific survival (DSS) rate.

resultsA total of 191 patients with pathologically confirmed NPC were included in this study, with 54 patients in the ICA invasion group and 137 patients in the no ICA invasion group. The ICA invasion group showed a worse prognosis compared to the no ICA invasion group (

conclusionsLocally advanced NPC patients with ICA invasion have a miserable outcome and NLR represents a significant prognostic factor that impacts treatment decisions and survival.

Indexed as

chemoradiotherapyinternal carotid artery invasionnasopharyngeal cancerprognosisprognostic factorsurvival

Identifiers

PMID39941853
PMCPMC11816255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.