Evidence map›Paper›PMID 39941784›Full record

ArticleCancers2025

Robotic Liver Resection for Hepatocellular Carcinoma: A Multicenter Case Series.

Silvio Caringi, Antonella Delvecchio, Maria Conticchio, Francesca Ratti, Paolo Magistri, Andrea Belli, Graziano Ceccarelli, Francesco Izzo, Marcello Giuseppe Spampinato, Nicola De'Angelis and 5 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Silvio CaringiDepartment of Surgery, Università Degli Studi Roma "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.ORCID 0009-0008-6007-8834
Antonella DelvecchioUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-7759-4340
Maria ConticchioUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
Francesca RattiHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, 20132 Milano, Italy.ORCID 0000-0002-8108-9064
Paolo MagistriUnit of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Andrea BelliUnit of Hepato-Biliary and Pancreatic Surgery, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, 80131 Napoli, Italy.ORCID 0000-0002-6252-573X
Graziano CeccarelliUnit of General Surgery, San Giovanni Battista Hospital, USL Umbria 2, 06034 Foligno, Italy.
Francesco IzzoUnit of Hepato-Biliary and Pancreatic Surgery, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, 80131 Napoli, Italy.ORCID 0000-0003-3093-5408
Marcello Giuseppe SpampinatoUnit of General Surgery, "Vito Fazzi" Hospital, 73100 Lecce, Italy.
Nicola De'AngelisUnit of Digestive and Hepatobiliary Surgery, Centre Hospitalier Universitaire Henri Mondor, 94000 Créteil, France.
Patrick PessauxDepartment of Visceral and Digestive Surgery, University Hospital of Strasbourg, 67000 Strasbourg, France.
Tullio PiardiUnit of Surgery, Hôpital Robert Debré, 51100 Reims, France.
Fabrizio Di BenedettoUnit of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Luca AldrighettiHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, 20132 Milano, Italy.ORCID 0000-0001-7729-2468
Riccardo MemeoUnit of Hepato-Biliary and Pancreatic Surgery, "F. Miulli" General Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-1668-932X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver resection is the standard treatment for resectable hepatocellular carcinoma (HCC). The advent of robotic surgery has extended its application in liver surgery, reducing post-operative complications without compromising oncological safety. This study is a retrospective series with the aim of analyzing the preoperative patient's and tumor's characteristics and evaluating intraoperative and post-operative data in terms of hospital stay, complications, and oncological radicality.

methodsData were collected from a multicenter retrospective database that includes 1070 consecutive robotic liver resections (RLRs) performed in nine European hospital centers from 2011 to 2023. Of the entire series, 343 liver resections were performed for HCC.

resultsA total of 247 patients (72.3%) had mono-focal lesions. Major hepatectomies and anatomical resections have been perfomed in 87% and 55% of patients, respectively. All 17 conversions (4.95%) were to the open approach. The operative mean time was 239.56 min and the estimated blood loss was 229.45 mL. The overall post-operative complication rate was 22.74%, but severe complications occurred in 4.08% of patients and one of them (0.29%) was reoperated on. The mean hospital stay was 5.82 days with a mean ICU stay of 0.9 days. Twenty-six resections (7.6%) were R1 parenchymal. Forty-six patients (4.08%) were readmitted to the hospital within 90 days after discharge and seventy-eight patients (22.74%) had disease recurrence. Total deaths included 36 (10.5%) patients with a 90-day mortality of 0.9%.

conclusionsRobotic liver resection for HCC is feasible and safe when performed in experienced centers by surgeons who have completed the learning curve.

Indexed as

hepatocellular carcinomaliver resectionsminimally invasive liver surgeryoncological outcomerobotic hepatectomyrobotic surgery

Identifiers

PMID39941784
PMCPMC11816241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.