ReviewJournal of clinical medicine2025
Fibromyalgia: Understanding, Diagnosis and Modern Approaches to Treatment.
Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fibromyalgia in cancer patients: a systematic review and clinical implications for integrated care.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- Article
- Article
- Pain Mechanisms in Fibromyalgia: An Integrative Narrative Review of Central, Peripheral, Neuroimmune, and Psychobiological Factors.Biomedicines · 2026Review
- Changes in the mechanical properties and pressure pain thresholds of muscles in patients with fibromyalgia and their relationship with clinical parameters: a case-control study.European journal of applied physiology · 2026Article
- Determinants of Perceived Treatment Effectiveness in Women with Fibromyalgia: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Sublingual Cyclobenzaprine Approval: Expanding Options for Fibromyalgia Management.Health science reports · 2026Article
- Article
- Pain-centered symptom-language co-occurrence networks differ between interstitial cystitis/bladder pain syndrome and fibromyalgia in Reddit patient discourse.Scientific reports · 2026Article
- Investigation of the Effectiveness of Mindfulness-Based Yoga Training in Individuals with Fibromyalgia: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- Post-Diagnostic Lifestyle Adaptations in Fibromyalgia: A Network and Cluster Analysis of Real-World Behavioral Patterns.Nutrients · 2026Article
- Conceptualisation of Empathy in Interactions Between Healthcare Professionals and People With Fibromyalgia Syndrome: A Mixed-Methods Study.Journal of clinical psychology in medical settings · 2026Article
- The Effects of a 12-Week Home-Based Adapted Physical Activity Intervention on Health-Related Physical Fitness in Adult Women with Fibromyalgia Syndrome: An Interventional Field Study.Journal of functional morphology and kinesiology · 2026Article
- The Effect of Intravenous Lidocaine Treatment on Sleep and Quality of Life in Fibromyalgia: An Observational Study.Journal of clinical medicine · 2026Article
- From pain mechanisms to functioning: a rehabilitation perspective on fibromyalgia.European journal of physical and rehabilitation medicine · 2026Article
- Psychiatric comorbidity patterns across disability-based fibromyalgia phenotypes.CNS spectrums · 2026Article
- Assessment of Awake and Sleep Bruxism in Fibromyalgia Patients with Temporomandibular Disorders.Journal of clinical medicine · 2026Article
- Editorial: Integrative approaches to fibromyalgia: advancing multidisciplinary management strategies.Frontiers in medicine · 2026Article
- Association Between Fibromyalgia and Lower Urinary Tract Pain and Storage Symptoms in Women: A Systematic Review and Meta‑analysis.Journal of pain research · 2026Review
- Sublingual Cyclobenzaprine: First Approval.Clinical drug investigation · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia (FM) is a chronic condition characterized by generalized musculoskeletal pain associated with other symptoms, especially sleep and mood disorders, fatigue, and cognitive dysfunctions. The etiopathogenesis of FM is not sufficiently known, and regardless of numerous research, the clinical presentation is nonspecific, which makes it difficult to approve a timely diagnosis and, subsequently, an adequate therapeutic approach. Genetic, hormonal, immunological, and environmental factors are cited as potential factors in the development of this condition. Diagnosis is based on a clinical approach and known diagnostic criteria, while additional methods, such as radiographic, magnetic resonance, or laboratory analyses, can be useful to exclude other conditions. The heterogeneity of FM significantly impacts both diagnosis and treatment, as it presents a wide spectrum of symptoms that vary in severity, combinations, and underlying contributing factors. This variability is a challenge for clinicians and requires a holistic, comprehensive, multidisciplinary, patient-centered approach. According to The European League Against Rheumatism (EULAR) from 2016, treatment begins with patient education and involves the simultaneous application of pharmacological and nonpharmacological treatments. The application of only pharmacological or nonpharmacological treatment is most often not successful. Due to differences in pain threshold, psychological factors, and comorbidities, patients may respond differently to the same interventions. Although there is no universal treatment, this review brings up the fact that the timely recognition of symptoms and a tailored treatment with a patient-centered plan can significantly improve the quality of life of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.