Effects of Anesthesia and Surgery on the Morphologic and Functional Development of the Premature Neonatal Brain: A Systematic Review and Meta-Analysis.

Annalena G U Heisel, Markus F Stevens, Marsh Königs, Faridi S Jamaludin, Kristin Keunen, Jorinde A W Polderman

Abstract readReview

In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Sodium Butyrate Attenuates Sevoflurane-Induced Impaired Myelination and Neurobehavioral Deficits in Neonatal Mice via the H3K9ac/BDNF/TrkB Pathway.CNS neuroscience & therapeutics · 2026
Article
Bioengineered human brain organoids and organ-on-chip platforms for exposure-aware assessment of developmental neurotoxicity induced by general anesthetics and sedatives.Frontiers in bioengineering and biotechnology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annalena G U HeiselDepartment of Anesthesiology, Location AMC, Amsterdam University Medical Centres, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0001-7576-1187

Markus F StevensDepartment of Anesthesiology, Location AMC, Amsterdam University Medical Centres, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.

Marsh KönigsDepartment of Pediatrics, Emma Children's Hospital, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

Faridi S JamaludinAmsterdam UMC Location University of Amsterdam, Medical Library AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-1452-1769

Kristin KeunenDepartment of Anesthesiology, Location AMC, Amsterdam University Medical Centres, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.

Jorinde A W PoldermanDepartment of Anesthesiology, Location AMC, Amsterdam University Medical Centres, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands.ORCID 0000-0002-2903-5990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anesthesiabraindevelopmentinfantsneonatalsurgery

Identifiers

PMID39941588

DOI10.3390/jcm14030918

PMCPMC11818576

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.