Evidence map›Paper›PMID 39941442›Full record

ReviewJournal of clinical medicine2025

Transcatheter Aortic Valve Implantation (TAVI) in Bicuspid Anatomy.

Dimitrios N Nikas, Lampros Lakkas, Katerina K Naka, Lampros K Michalis

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitrios N Nikas1st Cardiology Department, Ioannina University Hospital, 455 00 Ioannina, Greece.ORCID 0000-0002-8333-4879
Lampros LakkasDepartment of Physiology, Ioannina Medical School, 455 00 Ioannina, Greece.
Katerina K Naka2nd Cardiology Department, Ioannina University Hospital, 455 00 Ioannina, Greece.ORCID 0000-0002-9900-9659
Lampros K Michalis2nd Cardiology Department, Ioannina University Hospital, 455 00 Ioannina, Greece.ORCID 0000-0001-8834-4462

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bicuspid aortic valve (BAV) stenosis, a common congenital condition, presents unique challenges for transcatheter aortic valve replacement (TAVI) due to anatomical variations like cusp morphology, coexisting aortopathy and calcification. TAVI offers a viable option for BAV patients with refinements in technique and technology, though ongoing research is essential to optimize patient-specific approaches and long-term results. Key considerations for TAVI in BAV include precise valve sizing, positioning, and the need for rigorous pre-procedural imaging to mitigate risks such as paravalvular leak and stroke. Early results show TAVI's safety and efficacy are comparable to surgery, though BAV patients undergoing TAVI often are exposed to higher rates of post-procedural pacemaker implantation. Emerging data on next-generation self-expandable (SE) and balloon-expandable (BE) valves reveal that while both offer success in this complex anatomical aortic valve variation, gaps remain in the long-term durability and management of BAV-related aortopathy. This review examines the latest advancements in TAVI for BAV, emphasizing how specialized approaches and device selection address BAV's complexities.

Indexed as

aortic stenosisbicuspidTAVI

Identifiers

PMID39941442
PMCPMC11818256

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.