Evidence map›Paper›PMID 39941259›Full record

ReviewDiagnostics (Basel, Switzerland)2025

Ultra-High Contrast (UHC) MRI of the Brain, Spinal Cord and Optic Nerves in Multiple Sclerosis Using Directly Acquired and Synthetic Bipolar Filter (BLAIR) Images.

Paul Condron, Daniel M Cornfeld, Mark Bydder, Eryn E Kwon, Karen Whitehead, Emanuele Pravatà, Helen Danesh-Meyer, Catherine Shi, Taylor C Emsden, Gil Newburn and 3 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Paul CondronMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.ORCID 0000-0002-5427-0634
Daniel M CornfeldMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.ORCID 0000-0002-7488-7834
Mark BydderMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.
Eryn E KwonMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.
Karen WhiteheadMultiple Sclerosis Society, Gisborne-Tairāwhiti 4010, New Zealand.
Emanuele PravatàDepartment of Neuroradiology, Neurocenter of Southern Switzerland, 6903 Lugano, Switzerland.ORCID 0000-0002-5225-2993
Helen Danesh-MeyerMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.
Catherine ShiMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.
Taylor C EmsdenMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.ORCID 0009-0002-8026-2889
Gil NewburnMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.
Miriam ScadengMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.ORCID 0000-0002-9593-2956
Samantha J HoldsworthMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.ORCID 0000-0002-2929-1169
Graeme M BydderMātai Medical Research Institute, Gisborne-Tairāwhiti 4010, New Zealand.

Funding

Fred Lewis Enterprise Foundation NoneFriends of Mātai Blue Sky Fund NoneGE Healthcare NoneHugh Green Foundation NoneJN & HB Williams Foundation NoneManaaki Moves NoneMangatawa Beale Williams Memorial Trust NoneMātai Ngā Māngai Maori and Kānoa- Regional Economic Development & Investment Unit of New Zealand NoneMultiple Sclerosis Society of New Zealand NoneNeurological Foundation (New Zealand) NoneNZ P Pull NoneTrust Tairāwhiti None
6 · The paper itself

Abstract

In this educational review, the basic physics underlying the use of ultra-high contrast (UHC) bipolar filter (BLAIR) sequences, including divided subtracted inversion recovery (dSIR), is explained. These sequences can increase the contrast produced by small changes in T

Indexed as

bipolar filter (BLAIR)divided subtracted inversion recovery (dSIR) sequencegrayout signlogarithmic then subtracted inversion recovery (lSIR) sequencemultiple sclerosisultra-high contrast MRIwhite matter disease of the brainwhiteout sign

Identifiers

PMID39941259
PMCPMC11816702

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.