Evidence map›Paper›PMID 39941170›Full record

ReviewDiagnostics (Basel, Switzerland)2025

The Dynamic Evolution of Eosinophilic Esophagitis.

Amir Farah, Tarek Assaf, Jawad Hindy, Wisam Abboud, Mostafa Mahamid, Edoardo Vincenzo Savarino, Amir Mari

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Eosinophilic Esophagitis in the Middle East: Insight From a Comprehensive Systematic Review.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amir FarahDepartment of Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0009-0009-3522-7292
Tarek AssafDepartment of Surgery, Holy Family Hospital, Nazareth 1601001, Israel.
Jawad HindyThe Proteomic Unit, Bnai Zion Medical Center, Haifa 3339419, Israel.
Wisam AbboudDepartment of Surgery, EMMS Nazareth Hospital, Nazareth Hospital, Nazareth 1613101, Israel.
Mostafa MahamidDepartment of Internal Medicine, Meir Medical Centre, Kefar Sava 4428164, Israel.
Edoardo Vincenzo SavarinoDivision of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, 35122 Padua, Italy.ORCID 0000-0002-3187-2894
Amir MariFaculty of Medicine, Bar Ilan University, Ramat Gan 5290002, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory condition of the esophagus characterized by eosinophilic infiltration, and hallmark symptoms of esophageal dysfunction such as dysphagia and food impaction. Over the past three decades, EoE has been recognized as a distinct clinical entity, distinguished from gastroesophageal reflux disease (GERD) through advancements in diagnostic techniques, particularly endoscopy with biopsy. The rising global prevalence of EoE reflects enhanced diagnostic awareness, evolving criteria, and environmental along with lifestyle changes. The etiology of EoE is multifactorial, involving genetic predispositions, immune dysregulation, the gut microbiome, and environmental triggers, including dietary allergens and aeroallergens. Key mechanisms include a type 2 helper T-cell (Th2)-driven immune response, epithelial barrier dysfunction, and genetic variants such as

Indexed as

diagnosisEosinophilic esophagitismanagementPPI

Identifiers

PMID39941170
PMCPMC11816659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.