Evidence map›Paper›PMID 39941133›Full record

ArticleInternational journal of molecular sciences2025

AgNP-Containing Niosomes Functionalized with Fucoidan Potentiated the Intracellular Killing of

Nereyda Niño-Martínez, Kayla Audreyartha, Kaitlyn Cheung, Sol Melchor Parra, Gabriel Martínez-Castañón, Horacio Bach

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nereyda Niño-MartínezFaculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, Canada.
Kayla AudreyarthaFaculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, Canada.
Kaitlyn CheungFaculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, Canada.ORCID 0009-0002-9719-3840
Sol Melchor ParraEscuela de Ciencias, Universidad de las Americas Puebla, Puebla 72810, Mexico.
Gabriel Martínez-CastañónFacultad de Estomatología, Universidad Autonoma San Luis Potosí, San Luis Potosí 78290, Mexico.ORCID 0000-0003-4982-5225
Horacio BachFaculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, Canada.ORCID 0000-0002-7740-9299

Funding

Antibody Engineering and Proteomics Facility N/A
6 · The paper itself

Abstract

Intracellular pathogens represent a challenge for therapy because the antibiotics used need to diffuse into the cytoplasm to target the pathogens. The situation is more complicated in the mycobacteria family because members of this family infect and multiply within macrophages, the cells responsible for clearing microorganisms in the body. In addition, mycobacteria members are enclosed inside pathogen-containing vesicles or phagosomes. The treatments of these pathogens are aggravated when these pathogens acquire resistance to antibiotic molecules. As a result, new antimicrobial alternatives are needed. Niosomes are vesicles composed of cholesterol and nonionic surfactants that can be used for antibiotic encapsulation and delivery. The current study developed a systematic formulation of niosomes to determine the best option for niosome functionalizing for precise delivery to the intracellular pathogen

Indexed as

Anti-Bacterial AgentsLiposomesMacrophagesMetal NanoparticlesMycobacterium abscessusMycobacterium Infections, NontuberculousPolysaccharidesSilverAnimalsMiceAnti-Bacterial AgentsfucoidanLiposomesPolysaccharidesSilverfucoidanfunctionalizationglycopeptidolipidMycobacterium abscessusniosomesilver nanoparticlessingle-chain antibody

Identifiers

PMID39941133
PMCPMC11818696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.