Evidence map›Paper›PMID 39941121›Full record

ArticleInternational journal of molecular sciences2025

Therapeutic Potential of

Chan-Seong Kwon, Byeol-Eun Jeon, Ji-Eun Lee, Hyeon-Young Kim, Ryun-Young Kang, Keun-Hu Kim, Eun-Ju Lee, Ju-Yeon Jang, Tae-Jin Kim, Ho-Jin Shin and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chan-Seong KwonDepartment of Integrated Biological Science, Pusan National University, Busan 46241, Republic of Korea.
Byeol-Eun JeonDepartment of Integrated Biological Science, Pusan National University, Busan 46241, Republic of Korea.
Ji-Eun LeeDepartment of Integrated Biological Science, Pusan National University, Busan 46241, Republic of Korea.
Hyeon-Young KimDepartment of Molecular and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
Ryun-Young KangDepartment of Biological Sciences, Pusan National University, Busan 46241, Republic of Korea.
Keun-Hu KimDepartment of Biological Sciences, Pusan National University, Busan 46241, Republic of Korea.
Eun-Ju LeeDepartment of Biological Sciences, Pusan National University, Busan 46241, Republic of Korea.
Ju-Yeon JangDepartment of Biological Sciences, Pusan National University, Busan 46241, Republic of Korea.
Tae-Jin KimDepartment of Biological Sciences, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0001-7678-0478
Ho-Jin ShinDivision of Hematology-Oncology, Department of Internal Medicine, Pusan National University Hospital, Busan 49241, Republic of Korea.
Sang-Woo KimDepartment of Integrated Biological Science, Pusan National University, Busan 46241, Republic of Korea.

Funding

National Research Foundation of Korea 2020R1I1A2075060National Research Foundation of Korea 2022R1A4A5031503National Research Foundation of Korea 2022R1F1A1074989
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is characterized by the accumulation of immature myeloid cells and a differentiation block, highlighting the urgent need for novel differentiation-inducing therapies. This study evaluated

Indexed as

Cell DifferentiationCinnamatesIridoid GlucosidesLeukemia, Myeloid, AcuteMitochondriaPlant ExtractsReactive Oxygen SpeciesCell Line, TumorCell ProliferationHumansCinnamatesIridoid GlucosidesPlant ExtractsReactive Oxygen Speciesacute myeloid leukemia (AML)Adina rubella Hance (ARH) stemdifferentiationmitochondrial reactive oxygen species (mtROS)Picroside IIIplant extractsscreening

Identifiers

PMID39941121
PMCPMC11818474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.