Evidence map›Paper›PMID 39941086›Full record

ArticleInternational journal of molecular sciences2025

The Lower Concentration of Plasma Acetyl-Carnitine in Epicardial Artery Disease-A Preliminary Report.

Tomasz Urbanowicz, Paweł Gutaj, Szymon Plewa, Anna Olasińska-Wiśniewska, Ievgen Spasenenko, Beata Krasińska, Andrzej Tykarski, Krzysztof J Filipiak, Martyna Pakuła-Iwańska, Zbigniew Krasiński and 4 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tomasz UrbanowiczCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0001-8080-2764
Paweł GutajDepartment of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Szymon PlewaDepartment of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-9600-3980
Anna Olasińska-WiśniewskaCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-4213-8708
Ievgen SpasenenkoDepartment of Hypertensiology, Angiology and Internal Medicine, University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0009-0009-6993-4606
Beata KrasińskaDepartment of Hypertensiology, Angiology and Internal Medicine, University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-3464-1645
Andrzej TykarskiDepartment of Hypertensiology, Angiology and Internal Medicine, University of Medical Sciences, 61-701 Poznan, Poland.
Krzysztof J FilipiakDepartment of Hypertensiology, Angiology and Internal Medicine, University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-6563-0877
Martyna Pakuła-IwańskaDepartment of Hypertensiology, Angiology and Internal Medicine, University of Medical Sciences, 61-701 Poznan, Poland.
Zbigniew KrasińskiDepartment of Vascular, Endovascular Surgery, Angiology and Phlebology Medical University, Poznan University of Medical Science, 61-701 Poznan, Poland.ORCID 0000-0002-2798-1959
Ewelina GrywalskaDepartment of Experimental Immunology, Medical University of Lublin, Chodzki Street, 20-059 Lublin, Poland.ORCID 0000-0002-0451-4741
Ewa Wender-OżegowskaDepartment of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-5492-8651
Marek JemielityCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0003-2442-4644
Jan MatysiakDepartment of Reproduction, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-9993-1504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease remains an epidemiological challenge as global morbidity is not declining despite the fact that the risk factors are well known. Metabolomic derivatives of atherosclerosis formation have recently gained attention as a possible non-traditional risk factor. The aim of this study was to find potential differences in acetyl-carnitine chain serum concentrations between epicardial artery disease patients and a control group. There were 41 patients (25 men and 16 women), with a median (Q1-Q3) age of 69 (63-73) years, enrolled in the prospective metabolomic analysis. They were divided into two groups based on cine angiography results confirming epicardial artery disease (group 1,

Indexed as

AcetylcarnitineCoronary Artery DiseaseAgedBiomarkersCarnitineCase-Control StudiesFemaleHumansMaleMetabolomicsMiddle AgedProspective StudiesAcetylcarnitineBiomarkersCarnitineacetyl-carnitinecoronary artery diseasecoronary atherosclerosismetabolomic

Identifiers

PMID39941086
PMCPMC11818344

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.