Evidence map›Paper›PMID 39941082›Full record

ArticleInternational journal of molecular sciences2025

Cardiac Tyrosine 97 Phosphorylation of Cytochrome

Paul T Morse, Vignesh Pasupathi, Susanna Vuljaj, Nabil Yazdi, Matthew P Zurek, Junmei Wan, Icksoo Lee, Asmita Vaishnav, Brian F P Edwards, Tasnim Arroum and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paul T MorseCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0003-1530-1466
Vignesh PasupathiCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-3477-4659
Susanna VuljajCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.
Nabil YazdiCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.
Matthew P ZurekCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.
Junmei WanCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-5867-0694
Icksoo LeeCollege of Medicine, Dankook University, Cheonan-si 31116, Chungcheongnam-do, Republic of Korea.
Asmita VaishnavDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University, Detroit, MI 48201, USA.
Brian F P EdwardsDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University, Detroit, MI 48201, USA.
Tasnim ArroumCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.ORCID 0009-0004-9644-3494
Maik HüttemannCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0001-6310-7081

Funding

Development and Testing of LUCID: A Therapeutic Device for Brain Injury Following Infant Cardiac ArrestU44NS125160 · NINDS · MITOVATION, INC. · PI MAIK HUETTEMANN, Thomas Hudson Sanderson · 2022 to 2026
$3.6M
Non-invasive mitochondrial modulation therapy for ischemic strokeR01NS120322 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2021 to 2025
$2.3M
Non-invasive infrared light therapy and medical device to treat spinal cord injuryR01NS134695 · NINDS · WAYNE STATE UNIVERSITY · PI MAIK HUETTEMANN, Moh H. Malek · 2024 to 2026
$1.7M
Control of Cell Respiration and Apoptosis by Phosphorylation of Cytochrome cR01GM116807 · NIGMS · WAYNE STATE UNIVERSITY · PI HUETTEMANN, MAIK · 2017 to 2020
$1.5M
NIGMS NIH HHS R01 GM116807NIH HHS R01 GM116807NIH HHS R01 NS120322NIH HHS R01 NS134695NIH HHS U44 NS125160NINDS NIH HHS R01 NS120322NINDS NIH HHS R01 NS134695NINDS NIH HHS U44 NS125160
6 · The paper itself

Abstract

It was previously reported that tyrosine 97 (Y97) of cytochrome

Indexed as

ApoptosisCytochromes cMyocardiumTyrosineAnimalsCaspase 3CattleCell RespirationElectron Transport Complex IVFibroblastsMembrane Potential, MitochondrialMicePhosphorylationReactive Oxygen SpeciesCaspase 3Cytochromes cElectron Transport Complex IVReactive Oxygen SpeciesTyrosineapoptosis: reactive oxygen speciescytochrome cischemia-reperfusionmitochondrial respirationmyocardial infarction

Identifiers

PMID39941082
PMCPMC11818311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.