Evidence map›Paper›PMID 39941061›Full record

ArticleInternational journal of molecular sciences2025

The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer.

Albert Iñañez, Raúl Del Rey-Vergara, Fabricio Quimis, Pedro Rocha, Miguel Galindo, Sílvia Menéndez, Laura Masfarré, Ignacio Sánchez, Marina Carpes, Carlos Martínez and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Albert IñañezCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.ORCID 0009-0008-2493-0997
Raúl Del Rey-VergaraCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.ORCID 0000-0002-7973-0772
Fabricio QuimisCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.
Pedro RochaDepartment of Medical Oncology, Hospital del Mar, 08003 Barcelona, Spain.
Miguel GalindoCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.ORCID 0000-0002-0650-8660
Sílvia MenéndezCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.
Laura MasfarréCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.
Ignacio SánchezDepartment of Pathology, Hospital del Mar, 08003 Barcelona, Spain.
Marina CarpesInstituto Murciano de Investigación Biosanitaria IMIB-Pascual Parrilla, Pathology Core, 30120 Murcia, Spain.
Carlos MartínezInstituto Murciano de Investigación Biosanitaria IMIB-Pascual Parrilla, Pathology Core, 30120 Murcia, Spain.ORCID 0000-0003-3307-1326
Sandra Pérez-BuiraDepartment of Pathology, IIS-Fundación Jiménez Díaz-CIBERONC, 28040 Madrid, Spain.
Federico RojoDepartment of Pathology, IIS-Fundación Jiménez Díaz-CIBERONC, 28040 Madrid, Spain.
Ana RoviraCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.
Edurne ArriolaCancer Research Program, Hospital del Mar Research Institute, 08003 Barcelona, Spain.ORCID 0000-0001-8960-7519

Funding

Agència de Gestió Ajuts Universitaris de Recerca, Generalitat de Catalunya 2021 SGR 00776Fondo de Investigación Sanitaria PI19/00003Fondo de Investigación Sanitaria PI22/00105Instituto de Salud Carlos III PI24/00160Instituto de Salud Carlos III PT23/00114Instituto de Salud Carlos III (ISCiii) CB16/12/00241Instituto de Salud Carlos III (ISCiii) FI20/00001
6 · The paper itself

Abstract

Complex RNA-seq signatures involving the transcription factors

Indexed as

Basic Helix-Loop-Helix ProteinsGene Expression Regulation, NeoplasticLung NeoplasmsSmall Cell Lung CarcinomaTranscription FactorsAnimalsBiomarkers, TumorCell Line, TumorHumansMiceNeoplastic Cells, CirculatingReal-Time Polymerase Chain ReactionASCL1 protein, humanBasic Helix-Loop-Helix ProteinsBiomarkers, TumorNEUROD1 protein, humanTranscription FactorsASCL1NEUROD1POU2F3RT-qPCRSCLC subtypessingle-gene marker

Identifiers

PMID39941061
PMCPMC11818609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.